Melanotic neuroectodermal tumor of infancy (MNTI) is a rare infantile tumor that originates from mesenchymal-neuroectodermal cells, the treatment of which uses platinum derivatives that can affect hearing loss. The present study evaluated the long-term effects of ototoxicity following chemotherapy with cisplatin, vincristine, cyclophosphamide, teniposide and adriamycin in a 10-year-old patient after surgical removal of a MNTI tumor at the age of 8 months. Audiometric tests (high-frequency tonal audiometry, speech audiometry, speech acoustics, tympanometry and absorbance measurements) were performed during a 10-year follow-up after receiving chemotherapy. Hearing disorders in the high-frequency range (6,000 to 16,000 Hz range) were demonstrated for both ears, indicating that these may be the long-term effects of chemotherapy with use of platinum compounds during the treatment of infants. Case study This case study presents a long-term ototoxic effects after chemotherapy with cisplatin, vincristine, cyclophosphamide, teniposide and adriamycin in a 10-year-old female patient, who was administered this combination of drugs before and after surgical removal of MNTI at the age of 8 months. A female patient aged three months was admitted to the Department of Haematology and Paediatric Oncology of the Karol Jonscher Clinical Hospital in Poznan with a mixed mesenchymal-neuroectodermal MNTI, a solid tumor within the alveolar ridge. Histopathological examination

Convolutional neural networks (CNNs) are used in many areas of computer vision, such as object tracking and recognition, security, military, and biomedical image analysis. In this work, we describe the current methods, the architectures of deep convolutional neural networks used in CBCT. Literature from 2000-2020 from the PubMed database, Google Scholar, was analyzed. Account has been taken of publications in English that describe architectures of deep convolutional neural networks used in CBCT. The results of the reviewed studies indicate that deep learning methods employed in orthodontics can be far superior in comparison to other high-performing algorithms.

With the appearance of the first signs of aging on the face, including wrinkles, we begin to think about our external appearance in terms of its aesthetics and attractiveness. The aesthetics of the face is one of the components of health, so in the process of evaluating the aesthetics of the face it is essential not to omit a very important aspect, namely the condition of the oral cavity and teeth. Therefore, when thinking about aesthetic medicine, it is worth consulting a dentist to assess the condition of the mouth, check the muscle tone, bone health, proper occlusion, missing teeth or tooth decay. Interdisciplinary dental treatment including restorative dentistry, periodontics, dental surgery, orthodontics, prosthodontics and sometimes maxillofacial surgery can be a prelude to facial aesthetic medicine treatment. A beautiful, aesthetic smile is not only a smile without signs of aging, but especially one resulting from healthy oral cavity.

Aesthetic medicine is very popular among women and men as a tool to improve the external appearance, thereby increasing self-confidence and facilitating interpersonal contacts. No need for post-procedures convalescence, low invasiveness and documented effects make skin peels one of the most-chosen procedures offered by cosmetology and aesthetic medicine surgeries. Due to their variety and simplicity of the procedure, some of them can be successfully used at home. They allow to improve the overall condition of the skin – smoothing out superficial wrinkles, skin colour improvement, increase tension of the skin. Positive effects are noted not only by clinicians, but also by persons undergoing facial skin peels, as presented in the own study.