The article substantiates the need to search for new solutions to increase crop yield through the use of new fertilizers. One of the options was proposed in this article. During the operation of nuclear power plants, by products are formed in the form of inert gases, for example, an isotope nitrogen-16, or helium-3 and helium-4, or xenon-133 and xenon-135. They are quite difficult to filter out of the air. If they are filtered into the atmosphere, other gas formations will pass. Therefore, the design of a cryogenic unit was developed for their deposition on the walls of the pipeline (transfer to a liquid state). In this case, they are separated by using different temperatures. Each liquid mixture is placed in its container. In autumn, these mixtures are transported to agricultural fields and spreads out. Experiments have shown that the use of these mixtures can increase the potato yield by two times compared to the case of no use of fertilizers. When comparing the results of the research of the potato yield grown using manure from domestic animals and compost with the yield obtained using a liquid mixture of the noble gas, it was established that the yield is lower by 60 % and 40 %.