The results document a GYPA-B-A hybrid gene, probably produced via a single unequal homologous recombination event. A segmental transfer of GYPB seems most likely accounting for the allelic dropout.

IntroductionTo determine the effect of parental participation in hospital care on neonatal and parental outcomes in low- and middle-income countries (LMICs) and to identify the range of parental duties in the care of hospitalized neonates in LMICs.MethodsWe searched CINAHL, CENTRAL, LILACs, MEDLINE, EMBASE and Web of Science from inception to February 2022. Randomized and non-randomized studies from LMICs were eligible if parents performed one or more roles traditionally undertaken by healthcare staff. The primary outcome was hospital length-of-stay. Secondary outcomes included mortality, readmission, breastfeeding, growth, development and parental well-being. Data was extracted in duplicate by two independent reviewers using a piloted extraction form.ResultsEighteen studies (eight randomized and ten non-randomized) were included from seven middle-income countries. The types of parental participation included hygiene and infection prevention, feeding, monitoring and documentation, respiratory care, developmental care, medication administration and decision making. Meta-analyses showed that parental participation was not associated with hospital length-of-stay (MD −2.35, 95% CI −6.78–2.07). However, parental involvement was associated with decreased mortality (OR 0.46, 95% CI 0.22–0.95), increased breastfeeding (OR 2.97 95% CI 1.65–5.35) and decreased hospital readmission (OR 0.36, 95% CI 0.16–0.81). Narrative synthesis demonstrated additional benefits for growth, short-term neurodevelopment and parental well-being. Ten of the eighteen studies had a high risk of bias.ConclusionParental participation in neonatal hospital care is associated with improvement in several key neonatal outcomes in middle-income countries. The lack of data from low-income countries suggests that there remains barriers to parental participation in resource-poor settings.Systematic review registration[https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=187562], identifier [CRD42020187562].

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Integration concepts at the municipal level can be seen as an important step towards a Shared Society. The concept of Shared Society was developed against the background of increasing political and social polarization. A Shared Society means a stable and safe society where everybody feels at home and respected and has equal opportunities. Tolerance and diversity are key elements. This paper analyzes integration concepts of five German cities: Aachen, Frankfurt, Potsdam, Trier and Wiesbaden. It examines their strategies and explores how they could overcome previous assimilative approaches and contribute to a Shared Society. The comparative analysis is based on three key dimensions of a Shared Society: social cohesion, joint structures and enabling environment. We show how the application of the Shared Society concept could address current challenges in the field of migration and integration and discuss factors that drive Shared Society policies and practices in cities.

Description 5' PCM1 -3' JAK2. Transcript PCM1-JAK2 chimeric RNA constantly present; variable positions of the breakpoints within PCM1 and JAK2; reciprocal transcript may be present. Fusion proteinDiagrammatic representation of normal JAK2, normal PCM1 and the PCM1-JAK2 fusion protein.