Conventional resistive crossbar array for in‐memory computing suffers from high static current/power, serious IR drop, and sneak paths. In contrast, the “capacitive” crossbar array that harnesses transient current and charge transfer is gaining attention as it 1) only consumes dynamic power, 2) has no DC sneak paths and avoids severe IR drop (thus, selector‐free), and 3) can be fabricated on top of complementary metal–oxide–semiconductor (CMOS) circuits for 3D‐stacking. For the first time, ferroelectric Hf0.5Zr0.5O2 (HZO) capacitive crossbar arrays are experimentally demonstrated. Asymmetry of the HZO electrode interfaces leads to small‐signal capacitance on/off ratio >110% that can achieve read‐disturb‐free operation. The vector matrix multiplication (VMM) experiments are conducted on the fabricated capacitive crossbar array, showing a linear weighted sum versus numbers of input or on‐state weight. The array‐level VMM operation could maintain weight pattern reprogramming after 1) thousands of 1 ms/3 V pulses and 2) an extrapolated 10‐year retention at 85 °C. Array‐level circuit simulation at 22 nm node shows the energy consumption of a capacitive crossbar array is 20–200× lower than the resistive crossbar array counterpart. Moreover, analog‐shift‐and‐add circuits are designed for multibit weight summation, achieving 16.6% less area and 26.9% lower energy consumption than digital‐shift‐and‐add circuits.
Circular RNAs (circRNAs) are a class of non-coding RNAs with a circular, covalent structure that lack both 5' ends and 3' poly(A) tails, which are stable and specific molecules that exist in eukaryotic cells and are highly conserved. The role of circRNAs in viral infections is being increasingly acknowledged, since circRNAs have been discovered to be involved in several viral infections (such as hepatitis B virus infection and human papilloma virus infection) through a range of circRNA/microRNA/mRNA regulatory axes. These findings have prompted investigations into the potential of circRNAs as targets for the diagnosis and treatment of viral infection-related diseases. The aim of the present review was to systematically examine and discuss the role of circRNAs in several common viral infections, as well as their potential as diagnostic markers and therapeutic targets.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.