This research aims to determine the effect of strenuous physical activity on the sum of leukocytes. The study used experimentally with the posttest only control group design approach. The study subjects of 10 male mice were randomly divided into two groups. The control group was not given heavy physical activity and the treatment group was given heavy physical activity. On the 27th day of blood retrieval for an examination of the sum of leukocytes in the Integrated Biomedical Laboratory, in July-August 2020. The mean on the sum of leukocytes increased in the treatment group compared to the control group. The Mann Whitney test showed that the sum of leukocytes in the control group was significantly different from the treatment group with a value of p = 0.009 (p <0.05). More research is needed on strenuous physical activity in IL-6 levels and calculates leukocytes as one of the study boosters. This research can be used as a reference in the control of the immune system of the body.

Latar belakang: Masalah kesehatan yang sering timbul pada anak usia sekolah yaitu gangguan perilaku, penyakit infeksi, penyakit saluran pencernaan, penyakit saluran pernafasan, penyakit kulit, penyakit gigi mulut dan malnutrisi. Masalah-masalah tersebut timbul karena kurangnya pengetahuan serta kesadaran akan pentingnya kesehatan terutama kebiasaan mencuci tangan dan sikat gigi. Tujuan: untuk meningkatkan pengetahuan dan keterampilan guru dan siswa tertang cara sikat gigi yang baik dan benar dalam mencegah karies dentis. Metode: Kegiatan pengabdian masyarakat ini dilakukan dengan ceramah menggunakan media powerpoint dan LCD serta diskusi interaktif. Kegiatan diakhiri dengan pemberian pre-test dan post-test. Hasil: semua peserta mendapatkan peningkatan pengetahuan berdasarkan hasil pre-test dan post-test dengan rerata nilai post-test lebih tinggi dari nilai rerata pre-test peserta. Kesimpulan: Terjadi peningkatan pengetahuan tentang cara sikat gigi yang baik dan benar guna mencegah karies dentis. Kata kunci: karies dentis, penyuluhan, sikat gigi ________________________________________________________________________________________ Abstract Background: Health problems that often arise in school-age children are behavioral disorders, infectious diseases, digestive tract diseases, respiratory tract diseases, skin diseases, dental and oral diseases, and malnutrition. These problems arise due to a lack of knowledge and awareness of the importance of health, especially the habit of washing hands and brushing teeth. Objective: to increase the knowledge and skills of teachers and students about how to brush their teeth properly and correctly to prevent dental caries. Method: This community service activity is carried out with lectures using PowerPoint and LCD media and interactive discussions. The activity ended with a gift pre-test and post-test. Result: all participants received an increase in knowledge based on the results pre-test and post-test with the average value of the post-test being higher than the average value of the pre-test participant. Conclusion: there is an increase in knowledge about brushing teeth properly and correctly to prevent dental caries. Keywords: dental caries, counseling, tooth brushing