Anemia is one of the most nutritional problem in the world, including Indonesia. The World Health Organization (WHO) stated that the prevalence of anemia in the world reachs 40-88% and in Indonesia reach 26%. Anemia sufferers can decreased immunity, thus increasing the risk of being infected with the virus during the COVID-19 pandemic. The efforts to prevent anemia and increase body immunity have to be done, one of which is by eating food that rich in iron and immunomodulator sources. Therefore, BISNECO was created by formulation of mashed red dragon fruit, moringa leaves powder, and red ginger powder. It is an innovative biscuit that substituted with natural iron sources and immunomodulators. Biscuits as the most favorite snack of various people, such as children, adolescents, and adults with varoius economic conditions. BISNECO was made on baking principle, while the subtitients was made by drying and milling principle. The substituents were added to the biscuit dough and then baked at 120°C for 10 minutes. The Critical Control Points (CCPs) on BISNECO production are baking and cooling. The result of the analysis conducted showed that BISNECO has iron content as much as 29.064 mg/100 g with 22.836 mg/100 g degradated cause of baking process. If BISNECO consume as much as 100 grams for 21 consecutive days will increase Hb in the blood by 1.96 g/dl. BISNECO also contains 6-shogaol and 1-dehydro-6-gingerdion which effectively inhibit the production of nitric oxide and prostagladin E2 by activating macrophages to control immunity. Based on that role, BISNECO can prevent anemia and risk of Covid-19 infection. BISNECO is packaged in a multilayer standing pouch packaging with a zipper lock. The standing pouch packaging was made from polypropylene, aluminium, and enamel. It be done to keeps it’s quality and safety during the distibutions to consumers.