No abstract

Proficient writing performance in English requires multiple cognitive skills, which can be particularly challenging for English Learners (ELs). However, compared with reading and mathematics, there have been fewer scientific inquiries that explore the relationship between cognitive components and writing. The purpose of this study was to examine the role of three cognitive components (phonological awareness [PA], oral language development [OLD], and working memory [WM]), on writing development in Spanish-speaking EL children. To achieve this goal, 374 children in Grades 3 to 5 were administered a battery of cognitive measures in both Spanish as well as English, and a narrative writing task in English. Using structural equation modeling, three important findings emerged. First, the results showed that PA in both Spanish and English positively predicted English writing performance. Second, English OLD had a positive effect on writing, but Spanish OLD was a negative predictor of writing. Third, WM in both languages had large positive effects on writing in English. Taken together, the findings from this study highlight the important roles firstand second-language PA, OLD, and WM play in upper elementary ELs' English writing. Educational Impact and Implications StatementThe present study suggests that improving foundational cognitive components (i.e., phonological awareness, oral language, and working memory) may be beneficial in promoting writing for upper elementary English Learners who are receiving English-only instruction. It also highlights the roles of these cognitive components in the first language to writing. Additionally, this study provides a cognitive map for practitioners to identify specific skills needed to improve their student's writing development via instruction.

No abstract

Thrombocytes can be concentrated in blood derivatives and used as autologous transplants e.g. for wound treatment due to the release of growth factors such as platelet derived growth factor (PDGF). Conditions for processing and storage of these platelet-rich blood derivatives influence the release of PDGF from the platelet-bound α-granules into the plasma. In this study Platelet rich plasma (PRP) and Platelet concentrate (PC) were produced with a fully automated centrifugation system. Storage of PRP and PC for 1 h up to 4 months at temperatures between −20°C and +37°C was applied with the aim of evaluating the influence on the amount of released PDGF. Storage at −20°C resulted in the highest release of PDGF in PRP and a time dependency was determined: prolonged storage up to 1 month in PRP and 10 days in PC increased the release of PDGF. Regardless of the storage conditions, the release of PDGF per platelet was higher in PC than in PRP.

No abstract