Vitamin A palmitate was incorporated into a laboratory chow (150,000 IU/kg diet) and fed ad libitum to C3H/HeJ female mice inoculated with 1 times 10-6 C3HBA tumor cells, beginning the day of inoculation. Control female mice of the same strain similarly inoculated were fed the laboratory chow alone. Vitamin A did not affect rate for the first 19 days, after which growth rates were independent of treatment. Vitamin A-treated mice survived for significantly longer times than did control mice.

No abstract

Wound breaking strength was measured in Long-Evans rats in two settings: in one experiment animals received Compound 48/80 i.p. for 8 consecutive days, starting 1 day before infliction of wound and in the second experiment 48/80 was given for 6 days before wounding. Wound breaking strength was always measured on the seventh day after wounding. There was a significant increase in wound breaking strength in animals treated before incision was made, as compared to controls, saline-treated animals (p less than 0.01). When 48/80 was given one day before incision was made, the breaking strength was significantly decreased (p less than 0.0002). Possible explanation for these opposite results is discussed.

No abstract

Chondroma of the larynx is rare, but should be suspected in elderly patients with persistent voice changes or recurrent colds when carcinoma has been disproved. We report a patient with chondroma of the larynx. The diagnosis was established following complications associated with anesthesia for an unrelated ailment.