: Angiogenesis, the generation of novel blood vessels form pre-existing ones, is a prerequisite for the physiological expansion, reparation, and functioning of body tissues and systems. However it is also involved in some pathological inflammatory situations, such as oncologic and chronic degenerative disorders. A correct angiogenesis and neo-vascular response also accompanies wound healing, interaction with biocompatible materials and tissue regeneration. In this respect, natural products deriving from terrestrial and marine plants/organisms may prevent and even cure various angiogenesis-dependent disorders. Bioactive natural compounds with antioxidant and anti-inflammatory activities could concur to maintain an adequate vascularization and endothelial functions and to inhibit angiogenesis, thus controlling tumor development. This review aims to illustrate the role of some marine-derived compounds as anti-angiogenetic agents

Background: There has long been a lot of debate about the role of nutrition in the pathogenesis of cardio- vascular diseases. Monounsaturated and polyunsaturated fatty acids, especially n-3 PUFAs are the types of fat that favor metabolic markers and represent central components of the Mediterranean diet, which is considered an ideal dietary pattern with great cardio protective effect. Aim: This study aims to assess the influence of Mediterranean diet on lipid metabolism, compared to not-Mediterranean hypocaloric dietary patterns. Materials and Methods: This prospective clinical trial evaluated total cholesterol, LDL, HDL, and triglycerides and their modifications in a group of adults in relation to the two different kinds of diet: on the one hand the typical western dietetic pattern, characterized by higher intakes of red meat, dairy products and refined grains, low consumption of fruits and vegetables (L-diet), and the Mediterranean diet (M-diet).