Background Adverse drug event (ADE) reporting enhances early detection of risks associated with drug use. Pharmacists are uniquely suited to detect and report ADEs, but their contribution is diminished by under‐reporting. Objectives To assess pharmacists' knowledge and perceptions towards ADE reporting and to determine factors that improve or impede reporting using data from published survey articles using PRISMA. Methods A systematic review was conducted to identify published survey articles that assess pharmacists' knowledge of and attitudes towards ADE reporting. PubMed, CINAHL and Web of Science databases were searched. The following information was extracted from eligible articles: demographic factors, sample size, response rate, survey delivery, pharmacists' working setting, barriers and facilitators of ADE reporting. Results Only 68 survey articles were eligible to be included in the review (out of 820). The number of respondents ranges from 10 to 1870, and response rate varied between 10.5% and 100%. Pharmacists working in hospital settings and clinical pharmacists were more likely to report, to have better knowledge, favourable attitudes and familiarity with ADE reporting systems compared to pharmacists working in community settings. The main barrier towards reporting (recorded in >70% of the studies) was lack of confidence/basic knowledge of pharmacovigilance systems/concepts and ADE reporting process. Providing special training and education programmes related to pharmacovigilance concept was the most commonly mentioned factor to enhance reporting. Conclusion To improve ADE reporting by pharmacists, it is recommended to design and integrate educational interventions related to pharmacovigilance within the pharmacy curriculum or continuous education courses.

Introduction Necrotizing fasciitis (NF) is a rapidly progressive necrosis of the fascial layer with a high mortality rate. It is a life-threatening medical emergency that requires urgent treatment. Lack of skin finding in NF made diagnosis difficult and required a high clinical index of suspicion. The use of ultrasound may guide clinicians in improving diagnostic speed and accuracy, thus leading to improved management decisions and patient outcomes. This literature search aims to review the use of point-of-care ultrasonography in diagnosing necrotizing fasciitis. Method We searched relevant electronic databases, including PUBMED, MEDLINE, and SCOPUS, and performed a systematic review. Keywords used were “necrotizing fasciitis” or “necrotising fasciitis” or “necrotizing soft tissue infections” and “point-of-care ultrasonography” “ultrasonography” or “ultrasound”. No temporal limitation was set. An additional search was performed via google scholar, and the top 100 entry was screened. Results Among 540 papers screened, only 21 were related to diagnosing necrotizing fasciitis using ultrasonography. The outcome includes three observational studies, 16 case reports, and two case series, covering the period from 1976 to 2022. Conclusion Although the use of ultrasonography in diagnosing NF was published in several papers with promising results, more studies are required to investigate its diagnostic accuracy and potential to reduce time delay before surgical intervention, morbidity, and mortality.