This article brings the transcription and revision of the roundtable discussion held at the III Latin American Congress of Political Ecology, which aimed to debate different experiences of collective struggles against projects of extraction of natural resource, with the participation of indigenous leaders, traditional communities and activist intellectuals. The narratives shares experiences in processes in which there was collective resistance to extractive-colonial projects and the right to say “no” was put into practice. In general, the presentations discussed the right to say no that emerges beyond the right to consultation, and that has as its assumption the guarantee of collective autonomy over life territories.