A preocupação com as questões ambientais tem influenciado diretamente o desenvolvimento de novas tecnologias. A busca por um desenvolvimento sustentável tem levado a busca por metodologias que empreguem o conceito de Química Verde nos diferentes setores das Indústrias Brasileiras.  Nesta revisão, fazemos um breve relato da aplicação da Química verde no setor industrial Brasileiro.

The Nucleocapsid (N) protein is highlighted as the main target for COVID-19 diagnosis by antigen detection due to its abundance in circulation early during infection. However, the effects of the described mutations in the N protein epitopes and the efficacy of antigen testing across SARS-CoV-2 variants remain controversial and poorly understood. Here, we used immunoinformatics to identify five epitopes in the SARS-CoV-2 N protein (N(34–48), N(89–104), N(185–197), N(277–287), and N(378–390)) and validate their reactivity against samples from COVID-19 convalescent patients. All identified epitopes are fully conserved in the main SARS-CoV-2 variants and highly conserved with SARS-CoV. Moreover, the epitopes N(185–197) and N(277–287) are highly conserved with MERS-CoV, while the epitopes N(34–48), N(89–104), N(277–287), and N(378–390) are lowly conserved with common cold coronaviruses (229E, NL63, OC43, HKU1). These data are in accordance with the observed conservation of amino acids recognized by the antibodies 7R98, 7N0R, and 7CR5, which are conserved in the SARS-CoV-2 variants, SARS-CoV and MERS-CoV but lowly conserved in common cold coronaviruses. Therefore, we support the antigen tests as a scalable solution for the population-level diagnosis of SARS-CoV-2, but we highlight the need to verify the cross-reactivity of these tests against the common cold coronaviruses.

The Community Health Worker (CHW) has a vital importance for the Family Health Strategy (FHS). On the other hand, literature shows a gap in CHW education as well as in their professional education. This paper shows an in-running project, which aims to develop resources for the professional education of CHW using the social networks. Among the results, there is a Facebook ® webpage and some video material addressing important issues for CHW. Some of these videos are already available on YouTube ® . This content will be used as complementary educational resources with the CHW on Facebook ® webpage. A convenient sample from 15 CHW of the Cachoeiras de Macacu, a small village located in the state of Rio de Janeiro, were recruited to perform a preliminary assessment of three videos produced by the project. The content presented was the vaccination, the intestinal protozoa (some waterborne diseases) and the pediculosis. The evaluations were performed by psychometric Likert scale. All three videos obtained averages quite satisfactory on the content, professional importance and didactic. Thus, it is possible to infer a great potential of the use of this content through social networks. Besides the production these relevant content on topics of the Public Health, focused on the professional education of the CHW, the development of this project search to evaluate the potential application of social networks for Education in Health.

No abstract

Este artigo apresenta um estudo piloto de utilização das Redes Sociais Facebook e YouTube para a formação em serviço de Agentes Comunitários em Saúde (ACS), sobre temas da Hipertensão Arterial, no município de Aimorés – MG. No desenvolvimento de um processo educativo de caráter colaborativo e interprofissional, a estratégia de ensino desenvolvida ocorreu a partir das demandas de aprendizagem dos próprios ACS, relacionadas com os desafios de atendimento aos usuários da Atenção Básica em Aimorés. Foram produzidos 4 casos investigativos, uma videoaula e um processo exitoso de formação semipresencial de 5 ACS, com a participação de profissionais de três instituições públicas de pesquisa e ensino do país. Esse estudo pode contribuir nas discussões sobre formas de uso eficiente das Redes Sociais no desenvolvimento de processos educacionais e de trabalho interprofissional em Saúde no Brasil.