In this observational study, use of fluoxetine was associated with lower BOP percentages and reduced AL.

Mouth breathing has been reported to affect gingival health in children. However, studies on the effect of mouth breathing in adult patients are scarce. Objective: To examine the relationship between mouth breathing and gingival condition and to evaluate the distribution of gingival inflammation in young adult mouth breathing patients. Methods: Study groups comprised of participants with mouth breathing (test group) and nose breathing (control group) patients with gingivitis. Both the groups underwent periodontal examination. PI, GI and BOP % sites were recorded and analyzed statistically for the differences in mean values. Results: Mouth breathing patients showed higher full mouth GI and BOP scores. Upper anterior segment in mouth breathing patients showed highest GI and BOP followed by lower anterior segment, lower posterior and upper posterior region. Conclusion: Within the limits of present study, our findings suggest that relative to control group participants, test group i.e. patients with mouth breathing had higher gingival inflammation and bleeding sites in upper anterior region.

Abstract:We investigated the outcome of conventional periodontal treatment in mouth breathing patients with chronic periodontitis, and compared the efficacy of applying salivary substitute to the anterior sextants as an adjunct to conventional treatment in such patients. In this randomized, investigator-blind, clinical study involving parallel groups, 40 mouth breathing patients were divided into two groups: a control group (CG, n = 20) comprising patients who received scaling and root planing (SRP), and a test group (TG, n = 20) who received salivary substitute as an adjunct to SRP for treatment of chronic periodontitis. The patients were followed up at various time intervals, and improvement of the gingival index (GI) was examined as the primary outcome. Student's t-test, repeated-measures ANOVA and Mann-Whitney U test were applied for statistical analysis. Although periodontal parameters were improved in both groups after 8 weeks of follow-up, the test group showed better improvement in terms of GI and percentage bleeding on probing. Within the limits of this study, our results suggest that the use of salivary substitute has a beneficial adjunctive effect for improvement of periodontal parameters in mouth breathing patients with chronic periodontitis. (J Oral Sci 57, 241-247, 2015)

Background:A wide variety of drugs have the potential to affect immune and inflammatory responses of periodontium. A class of antidepressant drug, selective serotonin and norepinephrine reuptake inhibitors, has shown anti-inflammatory function. The aim of the present study is to explore the effect of desvenlafaxine on clinical periodontal parameters in patients with chronic periodontitis.Materials and Methods:The patients were divided into two groups as follows: test group (n = 63) comprised of participants on 50 mg once-daily dose of desvenlafaxine for ≥2 months and control group (n = 72) included participants who were yet to be prescribed medication for depression. Periodontal parameters of both the groups were analyzed and compared statistically.Results:Participants taking desvenlafaxine revealed lower values of periodontal parameters as compared to those in control group. The number of pockets with greater depth and clinical attachment loss was greater in control group.Conclusion:In our study, patients on desvenlafaxine were associated with less pocket depth and bleeding on probing.

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