Summary In a retrospective study, the prognostic value and individual merit of seven variables, used in routine examination of colic cases, were tested. The following variables proved to be significant in discriminating between horses which survived and those which died: heart rate (P<0.00005), packed cell volume (P<0.00005) and intensity of colic signs (P<0.0001).

An experimental study of duodenal obstruction was performed on four horses to determine the relation between the volume of accumulated fluid in the stomach and the degree of dehydration and acid-base disturbances. After a rapid increase, the production of fluid decreased slowly and ceased within 38 hours. The production averaged 0.3 I/ 100 kg body weight/hour. A continuing increase in packed cell volume was observed after the cessation of fluid production and the release of the obstruction. After the initial metabolic alkalosis, one horse had a metabolic acidosis, whereas two remained slightly alkalotic during the time of the duodenal obstruction. Acid-base values were within normal limits in one horse.

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