Background: Polypharmacy and inappropriate prescriptions are prominent prescribing issues among geriatric patients. Beer's criteria, Drug-Drug interaction of common OTC drugs and WHO essential drug lists have been developed to assist in the reduction of potentially inappropriate medications prescribed to geriatric patients. Objective: This study was carried out to find out the rational prescription of drugs in the geriatric patients and to also investigate Polypharmacy. Methodology: A retrospective study on rational drug prescribing pattern in geriatric patient was carried out using prescriptions issued to the geriatric patients, 65 years and above, attending the outpatient and inpatient department of various hospitals and clinics of Hyderabad. A total of 125 prescriptions were collected and analyzed by using Beer's Criteria. Results: In this study we observed that almost all prescriptions were with polypharmacy. Only 3% of drugs were prescribed on generic names and remaining all is on brand names. 11 (13.75%) prescriptions had one or more potentially inappropriate medicines from Beer's Criteria and in 9 (11.25%) prescriptions drug-drug interactions were ascertained according to drugdrug interactions of common OTC drugs. Conclusion: Prevalence of polypharmacy was high which is usually unavoidable in the geriatric patients. Extending clinical pharmacist services can significantly improve rational use of medicines in geriatric population.

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Background: One of the major outcomes of valvular heart disease have been chronic complications that in turn have led to the reduced quality of life of patients. These complications have indeed caused immense burden on the health care system and has led to increased mortality rate. Objective: To determine prevalence rate and to evaluate complications of valvular heart disease patients. Methods: This is a cross sectional-based study carried out in a single hospital in Hyderabad, India. The survey was carried out over a year in India. The source of data collection was through case sheets and lab reports. Results: Of the total 102 subjects, valvular diseases were more prevalent in the age group of 51-60 and females were found to be more affected than males. Complications were less or equal to no after the procedure of valve replacement was performed in patients with severe cases though some patients showed complications even after surgery, but were stable after a long time of monitoring. 1% of valve prolapse cases were seen and 3% deaths due to the disease. St.jude mechanical valve of different sizes, 19 EPR biological valve and aortic valve implants were majorly used for valve replacement procedure. Conclusion: The study concludes that valvular diseases are more prevalent in the age group 51-60, and females were more affected by valvular diseases than males. Hypertension and diabetes mellitus were found to be the major comorbidities in valvular heart disease patients.

The heed on natural medications and their usage have been expanding quickly as of late, even in regions where present day medication is accessible. Plant derived substances and herbal drugs ,recently attracted great interest towards their unique & vast applications. As medicinal herbs, have bioactive compounds in abundance & can be utilized in conventional and current medication. There has been an increasing demand for plant based medicines, health products, pharmaceuticals, food supplements. The Objective of this Study is to enlighten the various immune enhancing properties of ginseng & to deliver these immune strengthening properties of ginseng it has been formulated into a syrup dosage form. Formulation of syrup was designed by utilizing extracts of Panax Ginseng, Sucrose, Benzoin & required quantity of Distilled water. The prepared herbal syrup was evaluated for different physicochemical parameters like pH, color, odour, taste, density, specific gravity, viscosity and stability. A review of Panax ginseng chemical constituents present in various parts of Panax ginseng is given in the present article. This may be useful in discovering potential therapeutic effects & developing new formulations.