The present study explored the <i>Spilanthes acmella</i> Murr. for insecticidal principle, a plant of high value. The seed extract showed insecticidal activity against <i>Plutella xylostella</i>. Further, bioassay guided isolation of bioactive compounds resulted in insecticidal active molecule, which was identified with the help of ESI-MS and NMR. Highest activity of 95 - 100 percent was observed at low dose of 2 g/l with spilanthol, while 60 - 70 and 80 - 90 percent mortality at 5 g/l in crude seed extracts prepared in methanol and hexane after 48 hours exposure, respectively. LC₅₀ of 1.49, 5.14, 5.04, 11.75 g/l was observed with spilanthol, crude seed extract of methanol, hexane, deltamethrin, respectively. The findings indicate the potential of <i>S</i>. <i>acmella</i> with potent insecticidal toxicity for the management of <i>P. xylostella</i> and other insects of agricultural importance

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Plant based therapeutics play an important role in the public health care system of any nation. The plant Thevetia peruviana belongs to the family Apocynaceae. The plant have a significant place in traditional system of medicine of Central and South America and tropical Asia. A number of different classes of secondary metabolites are present in Thevetia peruviana including alkaloids, flavonoids, steroids, cardiac glycosides, terpenoids, tannins, saponins etc. Several researchers had identified various pharmacological activities in different parts of the plant viz. seeds, flowers, bark, fruits, leaves. This review covers detailed ethanopharmacology, toxicology and bioactivities of Thevetia peruviana. Copy Right, IJAR, 2017,. All rights reserved. …………………………………………………………………………………………………….... Introduction:-Our planet is home for enormous medicinal plants. Mankind use of medicinal plants is not new rather dates back to thousands of years. In fact, ancient man was very dependent on green plants for his day-to-day needs of medicaments. When a plant is designated as medicinal, it is implied that the said plant is useful as a drug or therapeutic agent or an active ingredient of a medicinal preparation. Recently the demand for plant based therapeutics has increased steeply because of many loopholes in modern system of medicine such as various side effects and high cost. Moreover, increasing knowledge of metabolic process and the effect of plants on human physiology has enlarged the range of application of medicinal plants. The therapeutic properties of medicinal plants are attributed owing to the presence of active principles such as alkaloids, flavonoids, glycosides, terpenoids, tannins, coumarins, saponins etc.Thevetia peruviana (pers) K Schum is a medicinal plant with wide array of pharmacological properties, but yet not received considerable scientific attention. The plant belongs to the family Apocynaceae and is commonly known as yellow oleander. The plant is native to Central and South America, especially Mexico, Brazil and West Indies but now frequently cultivated throughout the tropical including India and Srilanka as an ornamental plant.

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