Digital forensics is an essential aspect of cyber security and the investigation of digital crimes. Digital recordings are routinely used as important evidence sources in the identification, analysis, presentation, and reporting of evidence. There has recently been concern that images and videos cannot be used as solid evidence since they may be altered very quickly due to the abundance of technologies available for the gathering and processing of multimedia data. The main goal of this endeavour is to comprehend advanced forensic video analysis methods to assist in criminal investigations. We first propose the acquisition extraction analysis in a forensic video analysis framework that employs efficient video and image enhancement techniques for low-quality video that would be transferred through social media applications and for CCTV footage analysis. The reliability of digital video recordings is essential in forensic science and other criminal investigation fields. Digital video forensic analysis is a technique that constantly faces new challenges. Currently, videos are authenticated using a variety of parameters, including pixel-based analysis, frame rate analysis, bit rate analysis, hash value analysis, and, most importantly, metadata analysis. It was believed that the development of technology required the development of a new method for the verification of digital video recordings. In this review study, we made a novel attempt by reviewing the media. Information and structural analysis of video containers in the MP4 file format have been used to distinguish between real and altered videos.
Objective The purpose of this cross‐sectional study was to explore relationships between biomarkers of neural health, including brain‐derived neurotrophic factor (BDNF) and nerve growth factor (NGF), cardiorespiratory fitness and muscular strength, and depression, fatigue, and quality of life (QOL) in cancer survivors who are currently receiving either chemotherapy and/or radiation treatments (TM), or not receiving treatment (NT), while enrolled in a structured exercise program. Methods Physically active cancer survivors were recruited from the University of Northern Colorado Cancer Rehabilitation Institute. Age, height, weight, and body fat percentage (BF%) were obtained, and cardiorespiratory fitness and muscular strength were evaluated using peak oxygen uptake (VO2 peak) and estimated one‐repetition maximum, respectively. Depression, fatigue, and QOL were evaluated with the Beck Depression Inventory, Revised Piper Fatigue Scale, and Ferrans and Powers QOL Index Version III Questionnaire. Rested and fasted plasma BDNF and NGF concentrations were obtained using enzyme‐linked immunosorbent assays. Differences between groups were evaluated using an unpaired t‐test, and Pearson’s correlation was used to determine the relationship between BDNF and NGF, and cardiorespiratory fitness, muscular strength, and questionnaire scores. Data are presented as mean ± standard deviation and significance was defined as P < 0.05. Results Twenty‐four cancer survivors participated in the study and were divided into TM (n=12) and NT (n=12) groups. Time since treatment for NT was 10.2±8.6 months. No significant differences were observed between groups in physical characteristics, fitness measures, or survey scores. When all participants were grouped together, characteristics were age: 65.2±12.9 y, height: 167.1±8.0 cm, weight: 79.8±16.6 kg, BF%: 36.7±9.6%, VO2 peak: 25.8±6.9 mL/min/kg, chest press: 37.0±15.9 kg, leg press: 103.7±38.1 kg, depression score: 5.7±3.8, fatigue score: 3.2±2.2, and QOL score: 23.8±2.9. Concentrations of BDNF were significantly lower in TM (85.1±27.9 pg/mL) compared to NT (141.3±68.2 pg/mL; P=0.01); however, when TM and NT were combined, mean NGF concentrations were 5.0±0.7 pg/mL and there were no significant differences between TM and NT groups. Concentrations of BDNF and NGF were not associated with measures of cardiorespiratory fitness or muscular strength, or with depression, fatigue, or QOL. Conclusions Concentrations of BDNF were significantly lower in physically active cancer survivors currently undergoing cancer‐related treatment. Although these cancer survivors were participating in structured exercise, which is known to increase circulating BDNF concentrations, these rehabilitation programs may not completely protect individuals against cancer‐related treatment reductions in BDNF. Support or Funding Information University of Northern Colorado Faculty Research and Development Program
Objective The purpose of this double blind, randomized, study was to determine the effects of Longvida® Optimized Curcumin on time trial performance time as well as the inflammatory mediator C‐reactive protein (CRP) after 2 weeks of an intensified training program. Methods Healthy men and women (aged 18–40 y) were randomly assigned to placebo (PLA; n=11), Curcumin 1 (LV1; n=12) or Curcumin 2 (LV2; n=11) groups. Participants consumed capsules of rice flour placebo (1000mg/day) or curcumin (1000mg/day; Longvida 1 (LV1) or 1000mg/day Longvida 2 (LV2)) for 14 days, during a 2‐week intensified, cycle training period, which consisted of 3 training sessions per week. Each training session consisted of 6, 90 second stationary cycling sprints at 80–90% heart rate max (HRmax) followed by 180 seconds of low intensity cycling at 50–60% HRmax. Age, body mass index (BMI), percent body fat (BF%; BodPod, Cosmed, USA), and peak oxygen uptake (VO2peak) were assessed at the pre intervention time point (PRE). Time trial performance (16.1 km; TT) was obtained on a stationary cycle and resting and fasted serum was evaluated for CRP using an enzyme‐linked immunosorbent assay at both PRE and post intervention (POST) time points. Differences among groups were assessed using a one‐way ANOVA, and PRE and POST measurements among groups were assessed using a two‐way mixed model ANOVA. Data are presented as mean ± standard deviation with significance set at α=0.05. Results At PRE, there were no significant differences between groups with respect to mean participant characteristics (age: 24.8±4.2 y; BMI: 24.0±3.5; BF%: 20.55±8.90; VO2peak 42.07±8.90 ml/kg/min). TT performance significantly improved an average of 1.41±5.01% (p=0.05) when PRE times were compared to POST. Additionally, although not statistically significant, the average TT time change from PRE to POST was −205.67 sec for PLA, −2.17 sec for LV1, −105.32 sec for LV2. There were no significant group effects or group by time interactions for CRP (PLA: 3.2 ±3.4 mg/L; LV1: 0.7 ±0.9 mg/L; LV2: 1.2±01.3 mg/L). Conclusions The intensified training period elicited a significant improvement in TT performance. When taken daily, the dose of curcumin used in this study did not appear to provide additional performance related benefits. However, when compared to the existing literature, the dose and the timing of curcumin intake as well as the mode of the activity may be related to curcumin‐mediated improvements in performance. Support or Funding Information Verdure Sciences, Noblesville, IN
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