Hu et al. provided insight into the mushroom-shaped dry adhesives for future bioinspired dry adhesive designs. [4] Contrarily, researchers employed a bioinspired core-shell structure to exhibit enhanced antiwear and friction-reduction performance. [5] Li et al. used thermoplastic polyurethane (TPU) to fabricate bioinspired e-skin with excellent rheological behavior. [6] However, in all these studies, researchers mostly investigate dry adhesives. Anwer et al. developed textured composite surface with extremely high coefficient of friction (COF) on ice. [7] However, there is no emphasis on the presence of wet environment. Researchers could potentially employ the concept of biomimicry to influence technological fields where drainage of water is essential, such as tire treads, surgical grippers, etc. Researchers have identified the potential to remain stable on flooded surfaces in some tree frogs and torrent frogs with the help of their toe-pads. [8] The eighteen toes of frogs (four at each forelimb and five at each hindlimb) consist of disklike pads at the tip. [9] Their toe-pads consist of epithelial cells which are mostly hexagonal in shape (length ≈ 10 µm), [10] and separate from each other at the top. Figure 1 shows a schematic morphological structure of frog toe-pad and epithelial cells. Though small in quantity, there are also cells of pentagonal (23.1%) and heptagonal (16.1%) shape on the pad surface. [11,12] The existence of grooves (width ≈ 1 µm, height/ depth ≈ 10 µm) [10] over the pad distinguish these epithelial cells from other similar cells on the rest of the body. [9] Moreover, the surface of epithelial cells is covered with peg-like projections (diameter ≈ 0.2 µm), which are bordered by small channels (width ≈ 40 nm, height ≈ 0.2 µm). [3] The pores of mucous glands, scattered among these epithelial cells, produce the watery secretion that forms an essential part of the adhesive mechanism of each toe-pad. But in case of torrent frogs, this layer becomes demolished due to the presence of water. [9] From the studies [13,14] of ranid frogs (torrent living), it has been observed that the prismatic (epithelial) cells for most of the ranid species are elongated (deviated geometry from regular hexagonal shaped) in comparison to regular cells. Ratio of width to length is around 60% whereas it is 80-100% for normal prismatic cells which helped them to have more improved projection and thus make a larger contribution to provide better friction. [15,16] In this study, the dynamic friction performance of frog toe-pad inspired surface patterns is investigated in three folds. First, frog toe-pad morphology is mimicked, designed, and fabricated using 3D printing technology. Friction coefficients of the models are measured experimentally over a wet medium, with varying velocity, load, and sliding direction. Furthermore, time is recorded to reach a 5 mm height by the water flow through a steady model in another experimental setup. Second, numerical simulation is employed to study the contact area, sliding displacement...