Sida corymbosa plant is one of medicinal plants used in many parts of Africa, including Nigeria for the treatment of human diseases. The purpose of this work was to investigate the antioxidant effects of Sida corymbosa ethanolic leaf extract on rats administered carbon tetrachloride (CCl 4 ). One hundred and sixty male-rats between 170-180 g were used. They were grouped into 8 major groups (groups A-H) and 4 subgroups (A 1 -H 4 ) in each group making it 32 subgroups of 5 rats each. The major groups comprise A (positive control-normal rats giving feed and water only and left for 7-28 d), B (negative control-those administered CCl 4 only at 0.4 ml/kgbw and left for 7-28 d), C-H (treatment groups-those administered extract before and after CCl 4 administration at 5,000, 3,000 and 1,000 mg/kgbw for 7-28 d). Antioxidant assays were determined using UV-VIS spectrophotometer (model 752g, China). Results of serum antioxidant assays done revealed that levels of serum reduced glutathione (GSH), glutathione peroxidase (GPx), catalase (CAT), supraoxide dismutase (SOD) and total antioxidant capacity (TAC) increased significantly (P<0.05) in the treatment groups from 7-28 d, when compared with the negative control. Oxidative assay carried out showed that serum malondialdehyde (MDA) levels were significantly lower (P<0.05) in treatment groups than in negative control groups. These may be suggesting that the extract may have improved the antioxidant levels of the rats. Sida corymbosa ethanolic leaf extract may, therefore, have positive effects on antioxidant status of rats administered CCl 4 .

This study was conducted to assess the building coverage and environmental quality of residential area in Nkpor Uno Idemili North L.G, Nigeria. The study employed a descriptive survey design to find out level of compliance of buildings to planning regulations. One hundred and eighty (180) were interviewed using a modified instrument (questionnaire). The data collected were coded into SPSS and analyzed with descriptive statistics. The results showed that 72(40%) reported inadequate setback as a major effect of over built buildings, 55(30.6%) reported inadequate free air space, 37(20.6%) said inadequate ventilation and lighting. Also, the nature of drainage system provided in residential areas; 76(42.2%) has no drainage system, 70(38.9%) has close drainage system. The building coverage of residential houses in the study area; 60(33.3%) has their building falls under 51-75% for over built, 48(26.7%) has their building falls under 76-100% for overbuilt. For the factors influencing the percentage of area built upon, 57(31.7%) has greed and no money to acquire a large plot of land, 47(26.0%) has no land space to built their desirable house. Then, non adherence to provision of adequate ventilation and lighting in the residential houses in the study area affects the dwellers’ health and such factors can promote communicable diseases. In conclusion, it was observed that the compliance rate was not encouraging because the planning regulations recorded very low compliance as include set–back from property boundaries; inadequate free air space; lost of aesthetic values, and inadequate ventilation and lighting. Therefore, government should embark on enforcement of land use plan, and strategic plans for various towns and villages to accommodate its utilities and facilities.