This study demonstrates that there is a subset of children with ASDs who demonstrate clinically relevant epileptiform activity during slow-wave sleep, and that this activity may be present even in the absence of a clinical seizure disorder. MEG showed significantly greater sensitivity to this epileptiform activity than simultaneous EEG, 1-hour clinical EEG, and 24-hour clinical EEG. The multifocal epileptiform pattern identified by MEG in the ASDs typically includes the same perisylvian brain regions identified as abnormal in LKS. When epileptiform activity is present in the ASDs, therapeutic strategies (antiepileptic drugs, steroids, and even neurosurgery) aimed at its control can lead to a significa

A case of meningioma with subdural membrane formation, but without a collection of subdural haematoma, is presented. The histological picture of the membrane was similar to that found in a chronic subdural haematoma. Relevant literature is reviewed.

Minimally invasive procedures (multiple subpial transection, topectomy and amygdalahippocampotomy) were used to treat 24 patients with intractable seizures. The seizure foci were in both hemispheres in 3 patients, all 4 lobes of a hemisphere in 1 patient, 3 lobes of a hemisphere in 5 patients, 2 lobes of a hemisphere in 11 patients and the temporal lobe alone in 4 patients. The longest follow-up is 41 months, with a median of 18 months. Sixteen patients have a follow-up of more than 1 years, with excellent results in 10 (66%) and good in the remaining 6 (38%). There were no permanent complications. These results are encouraging, because the majority of the patients were poor candidates for surgery.

A computed tomographic (CT) stereotactic system that uses the principle of bringing the reference markers and the probe holder into the CT plane of the target is described. This eliminates the need for obtaining the Z coordinate and enables one to measure directly the X and Y coordinates. The use of an arc and of a rotary arc carrier permits one to approach the target from any point on the skull. Off-axial reconstruction permits visualization of the trajectory in both the coronal and the sagittal planes.