Background: Malignant skin tumors are an important public health problem. Exposure to UV radiation is a significant risk factor in the development of these tumors. The most common skin malignancies are basal cell and squamous cell carcinomas, which have an excellent prognosis and a relatively low mortality rate. Materials and Methods: A retrospective study was done on 46 cases with histopathological diagnoses of malignant skin tumors, over a period of two years, in a tertiary care centre in Bagalkot, with the primary objective to demonstrate distribution of cases according to age, sex and site of these tumors. Results: Malignant skin tumors were most commonly seen in the age group of 51 to 60 years (30.5%). Male to female ratio was 2.2:1. Squamous cell carcinoma (56.5%) was the most common tumor followed by basal cell carcinoma (21.7%), verrucous carcinoma (10.9%) and malignant melanoma (4.3%). Rare tumors such as sebaceous carcinoma and trichilemmal tumor were also noted in this study. Conclusion: Histopathology remains the gold standard for the diagnosis, management and follow-up of patients with malignant skin tumors.
Hepatocellular carcinoma (HCC) is the commontumor of the liver and the third most common cause of cancer-related mortality worldwide. Patients with HCC may have metastasis to different sites. Intrahepatic and extrahepatic metastases are found in (~50–75%). Lung and regional lymph nodes are the most commonly involved sites. Metastasis to bone, skin, and adrenal glands are rare. Orbit metastasis and intracranial invasion are extremely rare. We are presenting a case of HCC that metastasized to the orbital cavity. The patient presented with progressive proptosis of the eyeball with retrobulbar and intracranial invasion and involvement of the sub-scalp region. Based on the imaging findings, it was initially misdiagnosed as meningioma; however, histopathological examination of the biopsy specimen resulted in a definitive diagnosis of HCC metastasis. The present case reveals that the alternative diagnosis of metastasis must be considered when diagnosing retrobulbar lesions in patients with HCC.
Calcinosis cutis (CC) is deposition of calcium salts in the skin. It is of four types i) dystrophic, ii) metastatic, iii) idiopathic and iv) iatrogenic [1]. Idiopathic CC is cutaneous calcification of unknown cause with normal serum calcium. Subepidermal calcified nodule and tumoral calcinosis are idiopathic forms of calcification [2].
Introduction: Mucormycosis is an uncommon but fatal fungal infection occurring in compromised immune conditions mainly due to diabetic
ketoacidosis, organ transplantation. In recent times of COVID pandemic, increased cases of mucormycosis were being reported. To study Aim:
histopathological ndings in mucormycosis and access predisposing factors for it. T Material and Methods: his case series study was conducted
from december 2020 to may 2021 in S. Nijalingappa medical collage, Pathology Department and Miskin laboratory, Bagalkot .We collected 98
cases of mucormycosis , did histopathological study of biopsy specimens in haematoxylin and eosin stained slides, collected case details regarding
age, site, covid status of patient and associated co morbidities. Out of 98 Results: cases of mucormycosis reported, peak incidence is seen between
40 to 60 years of age, predominantly seen in males, 64.5% presented with post covid status, 42.5% associated with diabetes mellitus and
predominant site involved was nasal cavity and sinuses. Mucormycosis being opportuni Conclusion: stic infection is reported increasingly in
covid-19 cases owing to low oxygen, high glucose, cytokine storm and compromised immunity
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