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Introduction This study is part of a multi- country matched cohort study designed to estimate the risk of long term neurodevelopmental of children exposed to iGBS. The specific objective of this paper is to compare NDI across domains of iGBS survivors with a matched non-GBS group in our population. Methods Survivors of iGBS in a south Indian hospital were identified and recruited between January 2020 and April 2021. Cases were compared with age and gender matched non-GBS children. Participants were assessed using Bayley Scales of infant and toddler development (BSID-III), Wechsler Preschool and Primary Scale of Intelligence (WPPSI- IV), Wechsler Intelligence Scale for Children (WISC- V), Child behaviour checklist (CBCL) and Bruininks- Oseretsky Test of Motor Proficiency (BOT-2) depending on age. Results Our cohort comprised 35 GBS exposed and 65 matched non-GBS children, aged 1- 14 years. iGBS exposed group had 17 (48.6%) children with impairment in at least one domain compared to 25 (38%) in the non-GBS group [Unadjusted OR- 1.51, 95%CI 0.65- 3.46], 9 (26%) children with ‘multi domain impairment’ compared to 10 (15.4%) in the non-GBS group [Unadjusted OR- 1.90, 95% CI 0.69- 5.24] and 1 (2.9%) child with moderate to severe impairment compared to 3 (4.6%) in the non-GBS group [Unadjusted OR- 0.60, 95%CI 0.06- 6.07]. In the iGBS group, more children had motor impairments compared to the non-GBS group [Unadjusted OR- 10.7, 95%CI 1.19- 95.69, p= 0.034] Conclusion Children with iGBS seem at higher risk of developing motor impairments compared to a non-GBS group.

ObjectiveThis study aimed to understand the barriers and facilitators of a neonatal follow-up programme, as perceived by parents of infants born with hypoxic ischaemic encephalopathy (HIE).DesignThis study applied a qualitative study design using interpretative phenomenological analysis. It included focus group discussions, face-to-face in-depth interviews and telephonic interviews. Data were analysed using thematic content analysis.SettingNeonatal follow-up clinic of a tertiary hospital in South India. The study was conducted between March and December 2020.ParticipantsFive fathers and eight mothers of infants with HIE.ResultsParents of children with HIE are torn between two worlds—an atmosphere of support and one of criticism. Three main themes were identified: (1) neonatal intensive care unit (NICU) stay: distressful versus reassuring experiences; (2) parenthood: supportive versus unsupportive environments; and (3) neonatal follow-up: adherence versus non-adherence.ConclusionParents of children with HIE experience sociocultural barriers in the NICU, after discharge and during the follow-up period. These lead to a complex array of emotional and physical consequences that affect parenting and follow-up care.

Date Presented 04/22/2023 Low follow up rate of infants with perinatal asphyxia leads to inefficient early intervention of these children in developing countries. The reasons for this are discovered in this study and can be applied to improve the rate of follow up and therapy Primary Author and Speaker: Suja Angelin Chandrasekaran Contributing Authors: Hima B John, Benjamin Jeyanth Ross, Asha Arumugam, Indira Balan, Reema Samuel