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Introduction This study is part of a multi- country matched cohort study designed to estimate the risk of long term neurodevelopmental of children exposed to iGBS. The specific objective of this paper is to compare NDI across domains of iGBS survivors with a matched non-GBS group in our population. Methods Survivors of iGBS in a south Indian hospital were identified and recruited between January 2020 and April 2021. Cases were compared with age and gender matched non-GBS children. Participants were assessed using Bayley Scales of infant and toddler development (BSID-III), Wechsler Preschool and Primary Scale of Intelligence (WPPSI- IV), Wechsler Intelligence Scale for Children (WISC- V), Child behaviour checklist (CBCL) and Bruininks- Oseretsky Test of Motor Proficiency (BOT-2) depending on age. Results Our cohort comprised 35 GBS exposed and 65 matched non-GBS children, aged 1- 14 years. iGBS exposed group had 17 (48.6%) children with impairment in at least one domain compared to 25 (38%) in the non-GBS group [Unadjusted OR- 1.51, 95%CI 0.65- 3.46], 9 (26%) children with ‘multi domain impairment’ compared to 10 (15.4%) in the non-GBS group [Unadjusted OR- 1.90, 95% CI 0.69- 5.24] and 1 (2.9%) child with moderate to severe impairment compared to 3 (4.6%) in the non-GBS group [Unadjusted OR- 0.60, 95%CI 0.06- 6.07]. In the iGBS group, more children had motor impairments compared to the non-GBS group [Unadjusted OR- 10.7, 95%CI 1.19- 95.69, p= 0.034] Conclusion Children with iGBS seem at higher risk of developing motor impairments compared to a non-GBS group.

Cutaneous metastases from endometrial adenocarcinoma are ominous and are seldom seen, though metastases occurring at the local sites, such as pelvic and para-aortic lymph nodes, vagina, peritoneum, and lungs are well recognized. The zosteriform pattern of lesions is even more rare. Here, we describe an interesting case of a 60-year-old female with carcinoma endometrium, presenting with zosteriform cutaneous metastasis.

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