A simple and precise green synthesis method that has been used to synthesis of dihydropyrimidinone (DHPMs) derivatives. The reaction involves three-component one-pot condensation of an aromatic aldehyde, β-ketoester and urea in lemon juice. A large number of Dihydropyrimidinone (DHPM) derivatives were synthesized using urea, ethyl acetoacetate with electron rich as well as electron deficient aromatic aldehydes. The different type of aldehyde used like benzaldehyde, 4-Chliorobenzaldehyde, 4-methoxybenzaldehyde, anisaldehyde, cinnamaldehyde, and salicyaldehyde etc. The fruit juice like orange, amla, lime juice without processing is used as catalyst. The recrystallized products obtained were identified using physical and spectroscopic techniques UV-Visible, IR, 1 HNMR etc. The yield of these reactions were found comparatively good and in the range of (80-95%). The advantage of this method is to initiate green chemistry approach in new researchers. The excellent yield, short time, operational simplicity, and the avoidance of the use of organic solvents and friendly preparation etc are the importance of the present work.

Costuspictus (spiral ginger) commonly known as 'Insulin plant' was introduced from Mexico to India (kerala) very recently. The literature survey reveals that the fresh raw leaves should be consumed for anti-diabetic. Despite the preliminary studies the detailed phytochemical investigation has not been reported so far. Therefore, the rhizome extracts of costus pictus in different organic solvents (acetone, ethyl alcohol, chloroform, n-hexane and water). The five extract yielded by cold maceration procedure with the solvent Acetone, n-Hexane, Ethyl alcohol, Chloroform and Water. The maximum extract yield was obtain in ethyl alcohol cold extract which was preferably used for further to phytochemical studies, even though there was negligible difference in the presence of chemical constituents in the extract of samples. The ethanol extract of rhizome has shown maximum number concentration of secondary metabolites. Further phytochemical testing, The phytochemical Investigation reports revels that Insulin Plant 'Costuspictus' The preliminary phytochemical tests indicated the presence of steroids, alkaloids, glycoids, flavonoids, saponin, tannins, in the extracts of rhizome of C. Pictus. The test which gave a positive results are mentioned in above phytochemical tests. The further work will be carried out for investigation of rhizome ethanol extract by thin layer chromatographic and Column chromatographic analysis, and spectroscopic analysis like GC-MS, 1 HNMR. Based on the above results it is evident that the leaves of C. pictus have ant diabetic effect and must be developing remarkable interest and potential in the new researcher for future studies on diabetes mellitus.

The bioactive aromatic aldehyde,