Abstract-Due to the increase in the easy accessibility of computers and mobile phones alike, routing has become indispensable in deciding how computes communicate especially modern computer communication networks. This paper presents performance analysis between EIGRP and OSPFP for real time applications using Optimized Network Engineering Tool (OPNET). In order to evaluate OSPF and EIGRP's performance, three network models were designed where 1st, 2nd and 3rd network models are configured respectively with OSPF, EIGRP and a combination of EIGRP and OSPF. Evaluation of the proposed routing protocols was performed based on quantitative metrics such as Convergence Time, Jitter, End-to-End delay, Throughput and Packet Loss through the simulated network models. The evaluation results showed that EIGRP protocol provides a better performance than OSPF routing protocol for real time applications. By examining the results (convergence times in particular), the results of simulating the various scenarios identified the routing protocol with the best performance for a large, realistic and scalable network.