BackgroundHyperthyroidism is very common in older cats, but the etiopathogenesis is poorly understood. Decreased risk of hyperthyroidism has been reported in certain colorpoint breeds, and this observation previously has been hypothesized to result from relatively greater tyrosine availability for thyroid hormone production because of limited ability to convert tyrosine to melanin pigment. However, studies investigating a potential link between coat pigmentation and risk of hyperthyroidism are limited.ObjectiveTo identify associations between coat phenotype and hyperthyroidism by investigation of breed, coat color, and hair length as risk factors for the disease.AnimalsData were used from 4,705 cats aged ≥10 years, referred to a single veterinary teaching hospital (2006–2014) in the United Kingdom.MethodsRetrospective, epidemiological, cross‐sectional study using Bayesian multivariable logistic regression to assess risk factors for hyperthyroidism.ResultsBurmese (odds ratio [OR], 0.01; 0.00–0.23; P = .004), Tonkinese (OR, 0.05; 0.00–0.95; P = .046), Persian (OR, 0.21; 0.10–0.44; P < .001), Siamese (OR, 0.27; 0.12–0.61; P = .002), Abyssinian (OR, 0.04; 0.00–0.74; P = .031), and British shorthair (OR, 0.47; 0.28–0.79; P = .004) breeds had decreased risk of hyperthyroidism compared to domestic shorthairs. Longhaired, nonpurebred cats (OR, 1.30; 1.03–1.64; P = .028) were at increased risk of hyperthyroidism. Coat color/pattern was not associated with hyperthyroidism in nonpurebred cats.Conclusions and Clinical ImportanceWe identified decreased risk of hyperthyroidism in the Tonkinese, Abyssinian, and British shorthair breeds, identified an association between risk of hyperthyroidism and hair length, and confirmed decreased risk in Burmese, Siamese, and Persian breeds. Additional studies are warranted to further investigate these findings.

This study was carried out in the Department of Medicine, Rajshahi Medical College, in 2006-2007 to study the thyroid peroxidase (TPO) antibody level among hypothyroid patients and to find out the effects of L-thyroxine therapy in TPO-antibody titer. After thorough physical examination and relevant investigations, 100 patients of hypothyroidism were enrolled in this study. The selected patients were given L-thyroxine replacement therapy at a dose of 50-150 microgram/d. Before starting L-thyroxine, serum was collected from all patients to estimate anti TPO-antibody level. All patients were followed-up after 12-28 weeks of full dose of L-thyroxine therapy. Patients with high TPO-Abs at baseline, only 17.6% turned into euthyroid (based on composite clinical score), whereas about 42% of the patients who did not have high TPO-Abs became euthyroid suggesting that patients with high TPO Abs may show significantly poor response to treatment compared to the patients without high TPO Abs (p < 0.001). Patients with high TPO-Ab titers also showed a decreased biochemical response (TSH values) compared to the patients without high TPO-Ab positive patients. So, TPO-Ab plays a significant role in causation of the disease and is also associated with poor treatment response with L-thyroxine replacement therapy. TAJ 2018; 31(2): 45-49

Introduction: Anemia is a global public health concern, especially in lower and middle income countries like Bangladesh. The present study aimed to find out the hemoglobin level and prevalence of anemia among the patients admitted in a district hospital of Meherpur, Bangladesh. Methods: This cross sectional study was conducted among 500 patients admitted to Medicine and Gynecology department of Meherpur General Hospital. After enrollment, 2-3 ml of blood sample was collected in EDTA tubes from each patients and hemoglobin level was determined using an automated hematology analyzer for determination of anemia as defined by the WHO. All statistical analyses were carried out using SPSS version 24.0 for a significant p-value <0.05. Results: The mean (SD) age of the participants was 48.6 (18.9) years and almost 57% of them were female. Mean (SD) of the Hb level among the participants was 9.8 (1.7) g/dL which was significantly higher among men compared to women (10.1 mg/dL vs 9.5mg/dL). Overall prevalence of anemia was 93.8% (mild 25%, moderate 54% and severe 15%) and the prevalence was comparatively higher among women (96% vs 91%). Female sex and older age were significant risk factors of moderate to severe anemia among the participants though other variables like comorbidities and chronic NSAID use were not revealed as significant. Conclusion: Anemia prevalence was very high among the patients admitted in Meherpur district hospital, especially among female and elderly patients. So, routine assessment and proper management of anemia of the hospital admitted patients is crucial for better treatment outcome. TAJ 2021; 34: No-2: 114-121