Research  background  and  hypothesis.  Following  spinal  cord  injury  part  of  sympathetic  nervous  system is  disrupted  from  the  brain  stem  control,  which  results  in  cardiovascular  system  regulation  disorders.  Impaired cardiovascular regulation may cause orthostatic hypotension or other negative impacts on persons’ health. However, there are adaptive mechanisms which may change cardiovascular regulation and compensate these cardiovascular disorders. One of the mechanisms that may affect the occurrence of orthostatic hypotension may be changes in muscle tone after spinal cord injury.The aim of research was to ascertain the effect of muscle tone changes on blood pressure in persons with spinal cord injury through ortho-clinostatic test.Research methods. During passive ortho-clinostatic test, non-invasive blood pressure was continuously measured using the vital signs tracking monitor and leg muscle tone measurement was performed using myotonometer.Research results. In control group muscle tone is characterized as constant wave – it decreases in orthostasis and increases in clinostasis. In paraplegic group muscle tone changes are as similar to those in controls, except that dynamics is not so constant and numeric values are lower. In tetraplegics we can see that muscle tone changes rapidly and tone in thigh muscles has a tendency to decrease through all the test. Discusion and conclusions: 1. Leg muscle tone changes are important for blood pressure compensating mechanisms when the body position changes: it increases during orthostasis and decreases during clinostasis.2.  Blood  pressure  varies  differently  among  able-bodied  persons  and  persons  with  spinal  cord  injury.  The degree of the breach has a significant impact on the occurrence of compensatory peripheral regulation mechanisms. Characteristics  of  blood  pressure  fluctuations  during  body  position  changes  in  paraplegics  are  similar  to  those of reactions as in the able-bodied controls, while in tetraplegia case, possibilities of homeostatic blood pressure compensation during body posture changes are significantly reduced.

Cardiovascular response to the head-up tilt table test in the period when the vasovagal reaction emerges can reveal important information useful for diagnostic and preventive purposes. The aim of this study was to evaluate the influence of fatigue on the dynamics of functional cardiovascular parameters during the head-up tilt table test in non-athlete women cohort.A group of healthy non-athlete women attending health promotion training took part in the study (n = 20). In order to investigate the effect of post-workload parametric dynamics the subjects performed a 30-minute running sessions at a moderate intensity (aerobic exercising). Electrocardiography (ECG), arterial blood pressure (ABP) measurements were employed for the assessment of cardiovascular changes during an orthostatic test (head-up tilt table test) before and after the training session.The study results revealed significant differences in cardiovascular parameters analysed in this study: heart rate (HR), ST-segment depression, systolic, diastolic and pulse ABP before and after the workload (p < 0.05). In response to orthostasis an increase of the arterial blood flow intensity was indicated, while in response to clinostasis the decrease of arterial blood flow was observed. After the training session a post-workload hypotension was observed, and in response to orthostasis an increase of peripheral vascular tone was lowered. The results of the study confirmed that baroreflex regulation and autoregulation are sensitive to orthostatic body changes and could reveal the peculiarities of the cardiovascular functioning.