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Infectious and hazardous medical waste poses a deliberate threat to environmental health and needs special treatment and management prior to its ultimate disposal. Many of hospitals in Sylhet have neither a satisfactory waste management system nor a disposal policy. This study represents the present status of Hospital Waste (HW) management in Sylhet city, Bangladesh. A survey has been conducted using a questionnaire to collect information about the practices related to waste segregation, collection procedures, the type of temporary storage containers, on-site transport and central storage area, treatment of wastes, off-site transport, and final disposal options. Physico-chemical characteristics of medical wastes also have been determined according to standard methods. In developing nations like Bangladesh contrasted with developed countries, the management of infectious wastes has not received adequate consideration. The generation rate of medical waste is the key data for assessing and planning the transfer arrangement of medical waste. The waste generation rate of every unit in a hospital is diverse. The waste of every unit requires an alternate sort of analysis and treatment. It has been found that waste generation rates in government hospitals are higher than in private hospitals. Effective medical waste management programs are multispectral and require cooperation between all levels of implementation, from national and local governments to hospital staff and private organizations.