Internet of things (IoT) applications are becoming one of the emerging smart grid enabling technologies. Smart home appliances are one the beneficiary of such applications. Machine-to-Machine and Man-to-Machine are the basic IoT communication platforms that enable home appliances to communicate with each other to be more efficiently operated. In a recent search for the IoT communication protocols that are utilized in smart home appliances, there was no inclusive reference that contains and describes the smart home area networks and guides the research and development (R&D) professionals to select the suitable protocol for an application. This paper presents a comprehensive review of the home area network (HAN) communication protocols that are used to enable bidirectional communication between the home owners, utilities and smart home appliances. The paper presents the most utilized HANs wired and wireless communication protocols and discusses their characteristics, advantages and disadvantages. Index Terms-ZigBee, Wi-Fi, RFID, power line carrier, SPI, I 2 C RS485 I. INTRODUCTION One of the most important and rapidly evolving the technologies in electrical power system is the smart grid. The smart grid is a system of systems that integrates information and communication networks technologies with the traditional electrical power grid. This integration empowers utilities and consumers with bidirectional power flow and communication to better monitor, control and manage electrical power generation, transmission, distribution and consumption. From the communication point of view, the smart grid conceptual model consists of three major communication networks namely; wide area networks, local area networks and consumer area networks. Each one of these networks serves one of the electrical power domains namely; bulk generation and transmission domain, distribution domain and customers' domain respectively. Fig. 1 shows the smart grid communication networks that are mapped with the aforementioned electrical power grid domains [l]-[3]. The wide area network consists of the following sub communication networks:
This study investigated the occurrence of four non-steroidal anti-inflammatory drugs (NSAIDs) and four benzodiazepines/anti-depressants (ADs) in municipal wastewater in Mardan city, Pakistan, and in River Kabul and River Indus receiving untreated sewage. Liquid chromatography with a triple quadrupole tandem mass spectrometry (LC-MS/MS) was used for the analysis of paracetamol, diclofenac, ibuprofen, and codeine (NSAIDs) and diazepam, bromazepam, lorazepam, and temazepam (ADs). Except codeine and lorazepam, all the target compounds were observed in sewage and surface water in various concentrations. In sewage, paracetamol was found at the higher end (32.4 μg/L) of the reported ranges in literature for other countries. Results of river samples showed that the target compounds were usually lower in concentration than the respective EC values for aquatic organisms. However, the levels for paracetamol and ibuprofen were critical depicting the consequence of untreated disposal. Environmental risk assessment by estimating the risk quotient (RQ) as the ratio of measured environmental concentration and predicted no-effect concentration showed medium to high (RQ > 1 and 0.1 < RQ < 1) risk from paracetamol and ibuprofen to aquatic organisms in River Kabul and Kalpani stream, Pakistan.
Classical homocystinuria, also known as cystathionine beta synthase deficiency, is a rare disorder of methionine metabolism, leading to an abnormal accumulation of homocysteine and its metabolites in blood and urine. A young child with homocystinuria is discussed, who presented with behavioral abnormalities, involuntary movement, mental retardation, and decreased vision since birth. The diagnosis of homocystinuria was not made at initial presentation. Subtle phenotypic features with developmental delay and MRI brain finding of bilateral medially dislocated lens, eventually provided the first indication at five years of age. Laboratory screening with plasma amino acid profile by ion exchange chromatography (IEC) showed elevated homocystine and methionine, and low cystine in plasma in the absence of vitamin B12, and folate deficiency; giving the diagnosis of classical homocysteinuria.
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