Antimicrobial resistance (AMR) is a global health challenge and antimicrobial use (AMU) in the livestock sector has been considered as one of the contributing factors towards the development of AMR in bacteria. This study summarizes the results of a point prevalence survey conducted to monitor farm-level AMU in commercial broiler chicken farms in Punjab and Khyber Pakhtunkhwa (KPK) provinces of Pakistan. A cross-sectional study was conducted to quantify AMU and to check seasonal variations of AMU in 12 commercial broiler chicken farms (six from each province) during the summer and winter seasons of the year 2020–2021. AMU was recorded using three AMU metrics: kg, mg per population correction unit (mg/PCU), and mg/kg of final flock weight. A total of 22 antimicrobial drugs (348.59 kg) were used for therapeutic or prophylactic purposes in surveyed broiler chicken farms. The total combined AMU for all the broiler chicken farms was 462.57 mg/PCU. The use of most of the antimicrobials increased during winter flocks compared to summer. The top three antimicrobial drugs used during the summer were neomycin (111.39 mg/PCU), doxycycline (91.91 mg/PCU), and tilmicosin (77.22 mg/PCU), whereas doxycycline (196.81 mg/PCU), neomycin (136.74 mg/PCU), and amoxicillin (115.04 mg/PCU) during the winter. Overall, 60% of the antibiotics used in broiler chicken were critically important antimicrobial classes (CIA) for human medicine as characterized by the World Health Organization. Our findings showed high AMU in broiler chicken production and a call for urgent actions to regulate CIA use in food animals in Pakistan. This baseline survey is critical for the design and implementation of a subsequent national level AMU surveys that can include additional farming types, animals’ species, and geographical locations over a longer period of time.

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Carpal tunnel is the narrow space which is present between smaller bones of hand and an important ligament of hand which is called transverse carpal ligament. Compression of median nerve occurs commonly at wrist which results in Carpal Tunnel Syndrome (CTS). Objective: To compare effectiveness of median nerve mobilization with and without transverse carpal ligament stretching in patients with carpal tunnel syndrome. Methods: In this study, 34 patients were randomly assigned into one of two groups, each with 17 individuals. For two weeks, group B received a combination therapy strategy of Neurodynamics and transverse carpal ligament stretching, while group A only received neurodynamics. After two weeks, there was an improvement in functioning and pain. The DASH questioner and VAS were filled at baseline. The current RCT was conducted at the Akhtar Saeed Trust Hospital in Lahore. SPSS was used to conduct the analysis. Results: In the present study of 34 patients independent sample t test was applied as the mean difference was less in group B, which used a combination treatment method of transverse carpal ligament stretching and neurodynamics, compared to group A, which used only neurodynamics. The p value is less than 0.05, indicating that the results were significant. In comparison to group A, results of group B in which combined treatment approach was applied found to be more substantial and superior. Conclusions: Group B, which included both neurodynamics and transverse carpal ligament stretching, was shown to be more effective than group A, which solely used neurodynamics.

The quality of life in employees is an issue that must be examined as it is a crucial point for organization or industry growth. This study aims to investigate the correlation between professional quality of life with physical and psychological health in textile sector employees. Study was conducted on (N=150, male and female employees) employees from 19 textile companies in Lahore city, Pakistan. A correlational research design was used, and sample was selected by using stratified sampling technique. A series of questionnaire (Professional Quality of life and (SF-12) Short Form-12 Health survey) was administered to employees after taking consent from the them. The results indicate that quality of life has relationship with physical and psychological health. Specifically, compassion satisfaction aspect has positive significant relationship with physical and mental health component while inverse relationship with burnout and compassion fatigue. When compassion satisfaction increases, the physical and psychological health of the workers improved and vice versa. Similarly, when burnout and compassion fatigue increase, it affected the physical and psychological health of the workers. It is recommended to the organization to make plans and policies to boost up employees mental and physical health. Kualitas hidup karyawan merupakan masalah yang harus diperhatikan terutama dalam dunia kerja. Penelitian ini bertujuan untuk mengetahui hubungan antara kualitas hidup professional dengan kesehatan fisik dan psikologis pada karyawan sektor tekstil. Studi dilakukan pada (N=150, karyawan pria dan wanita) karyawan dari 19 perusahaan tekstil di kota Lahore, Pakistan. Rancangan penelitian yang digunakan adalah korelasional, dan sampel dipilih dengan menggunakan teknik stratified sampling. Serangkaian kuesioner (Professional Quality of life dan (SF-12) Short Form-12 Health survey) diberikan kepada karyawan setelah mendapat persetujuan dari mereka. Hasil penelitian menunjukkan bahwa kualitas hidup memiliki hubungan dengan kesehatan fisik dan psikologis. Secara khusus, aspek compassion satisfaction memiliki hubungan positif yang signifikan dengan komponen kesehatan fisik dan mental, sedangkan hubungan terbalik dengan burnout dan compassion fatigue. Ketika compassion satisfacion meningkat, kesehatan fisik dan psikologis pekerja meningkat dan sebaliknya. Demikian pula ketika burnout dan compasison fatigue meningkat, hal itu mempengaruhi kesehatan fisik dan psikologis para pekerja. Disarankan kepada organisasi untuk membuat rencana dan kebijakan untuk meningkatkan kesehatan mental dan fisik karyawan.