It is critical to protect coastal and offshore structures. Most current studies and scientific investigations are centered on how to protect seashore with an efficient and cost-effective system. This study involved the testing of a new floating breakwater configuration (FB). A series of experiments were carried out in the lab of The Higher Institute of Engineering (El-shorouk City) on the new model and the traditional vertical plane FB without a curved face to compare their behaviours and performance in wave attenuation. The incident, reflected, and transmitted wave heights were measured, and the coefficients of reflection, transmission, and energy dissipation were calculated using these measurements. In terms of hydrodynamic performance, the curved-face floating breakwater outperformed the traditional vertical floating breakwater, according to the study's highlights. The curved face model significantly reduced wave transmission values when compared to the traditional vertical configuration. The greater the concavity of the curve, the better the model handles waves, especially when the wave steepness is low.
Background Acne vulgaris is a worldwide dermatological condition that has a complex pathophysiology in which androgens play an important role. Flutamide is a first-generation non-steroidal antiandrogen that can be used for acne treatment. Aim To evaluate the potential therapeutic efficacy and safety of topical flutamide in the treatment of acne vulgaris. Methods A andomized controlled study included two equal groups, each had 27 patients, with a total of 54 patients with mild to moderate acne vulgaris having inflammatory (papules and pustules) and non-inflammatory (comedones) lesions. For eight weeks, Group (A) received 1% Flutamide topical gel on the face twice daily, whereas Group (B) served as the control group. Result After 8 weeks of topical Flutamide 1% gel application twice daily, there was a significant reduction in papules count, and a highly significant reduction in pustules number from baseline. Limitations We recommend that topical Flutamide 1% gel be tried on a larger number of patients with acne vulgaris, for longer therapeutic duration and follow up periods after treatment. Conclusion Patients with acne vulgaris may find topical Flutamide 1% gel to be a viable, efficient, and safe solution with few adverse effects.
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