Coarctation of the aorta (CoA) is a common Congenital Heart Disease (CHD) presenting with many symptoms and signs, in any age group. From its dramatic appearance as a part of Hypo plastic Left Heart Syndrome (HLHS), to early Congestive Heart Failure(CHF)in neonatal and early infantile age, to undetected Hypertension (HTN) in early or even late adulthood. The aim of this short review is to present this unique CHD, underline the presentation of late detected CoA, presenting with HTN and its impact in treating resistant HTN even after successful surgical treatment. Finally, the late onset HTN, following successful surgical treatment and its medicine management will be addressed. This difficult to control on mono or dual pharmacotherapy and the late complications of persistent uncontrolled HTN is the basic reason that these patients are a long-life follow-up population with important medical needs and increasing morbidity and mortality. Abriviations

Diabetes mellitus is a relatively common illness that can complicate pregnancy and result in an increased incidence of congenital malformations. Offspring of diabetic mothers suffering from type IDDM have a fivefold incidence of congenital malformations compared to pregnancies in the general healthy population. Specifically, the pattern of congenital heart disease (CHD) encountered among this group, with an emphasis on abnormalities of laterality, looping and conotruncal septation, suggesting that the maternal metabolic state affects cardiogenesis at a very early stage of the developmental period, prior to 7 weeks of gestation. Although many have been written on the effect of diabetes in pregnant women, less is known for the effects of type II DM and gestational diabetes mellitus (GDM) and its role in provoking CHD. Aim of this paper is to review the literature regarding the types of CHD seen in offspring of mothers suffering from different types of diabetes mellitus, maternal types 1 and 2 and gestational and to comment on the incidences and any differences found in the types of detected CHD.

Coarctation of the aorta (CoA) is a common Congenital Heart Disease (CHD) presenting with many symptoms and signs, in any age group. From its dramatic appearance as a part of Hypo plastic Left Heart Syndrome (HLHS), to early Congestive Heart Failure(CHF)in neonatal and early infantile age, to undetected Hypertension (HTN) in early or even late adulthood. The aim of this short review is to present this unique CHD, underline the presentation of late detected CoA, presenting with HTN and its impact in treating resistant HTN even after successful surgical treatment. Finally, the late onset HTN, following successful surgical treatment and its medicine management will be addressed. This difficult to control on mono or dual pharmacotherapy and the late complications of persistent uncontrolled HTN is the basic reason that these patients are a long-life follow-up population with important medical needs and increasing morbidity and mortality.