The aim of this study is to investigate the efficiency of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) gel and resin infiltrant on decalcified enamel, and to explain the correlation, if any, between ion release capacities and shear bond strength (SBS). A total of 80 premolar teeth were used (n=20). Group I was the control, while a demineralization protocol was performed for other groups. CPP-ACP gel and resin infiltrant, respectively, was applied to Groups III and IV. Pre and post-demineralization energy dispersive X-Ray analysis of all groups and post-application of Groups III and IV were undertaken. SBS tests were performed. Ca/P ratio significantly increased after the applications. Both agent groups showed a significant decrease in SBS values compared to others. There was no correlation between SBS and Ca/P ratio changes. It can be said that CPP-ACP and resin infiltrant therapies enhance the tooth mineral content, but show lesser SBS values than the control and demineralization only groups.
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