Elephantiasis is generally detected through microscopic examination of blood. Until now, this has been difficult because microfilariae only appear in the blood at night for a few hours (nocturnal periodicity). The lack of trained microscopy technicians is a serious problem. Due to the repetitive and tedious nature of diagnosis and the fact that there are few positive cases in a population of thousands. This is a contributing factor to increased detection errors. The main problem encountered is the high degree of difficulty and precision and the long time it takes to perform laboratory examinations. Image analysis method can be used as a way to identify Lymphatic Filariasis worms in the blood. Based on the description above, it can be said that the detection of Lymphatic Filariasis worms can be done with digital image analysis. This research will use the feature extraction method and Convolutional Neural Network to identify object features in the form of worms that cause elephantiasis (Lymphatic Filariasis) in digital images recorded by Trinocular digital microscope cameras. This study aims to determine the performance of image analysis methods used in the identification process of Lymphatic Filariasis worms using digital images recorded by a Compound Trinocular microscope.

Background: Physical exercise can improve antioxidant defense system of organis. But long and heavy exercise can disrupt the balance of oxidant-antioxidant. Low glutathione peroxidase is associated with free radicals. Plant purple sweet potatoes (Ipomoea batatas L.) contain anthocyanins high enough that act as antioxidants. This study aimed to determine the effect of extracts of tubers of purple sweet potato (Ipomoea Batatas L.) on the activity of glutathione peroxidase (GPx) liver of mice (Mus Musculus) treated with maximal physical exercise. Subjects and Method: This was a true experimental study. This conducted with the design of the control group post-test only in vivo on 24 white male mice (Mus musculus), DD Webster strain. Data analysis was using SPSS software 19. Statistical testing decision taken 5% significance level (p=0.05). Results: The results showed that the average enzyme activity of GPx in the P5 is the highest enzyme activity GPx (mean=19:39 ± SD=7:06, p=0.024), which means there are significant differrences in the enzyme activity of GPx values between groups. Conclusion:This study showed that the extract could increase the activity of GPx hepatic enzymees mice significantly.

Background: Heavy physical exercise can reduce blood flow and metabolism in kidney that eventually release free radicals. The free radicals can form oxydative stress and damage renal tissue. Exogenous antioxydant administration is usually recommended to minimize the renal tissue damage. This study aimed to examined the effect of purple sweet potato (Ipomoiea batatas L.) extract on renal tissue damage in mice (mus musculus L.) after heavy physical exercise. Subjects and Method: This was a randomized controlled trial with post test only control design. The study subjects included twenty four male white mice with DD Webster strain. These mice were divided into six groups. After undergoing excessive swimming exercises that lasted forteen days, purple sweet potato extract was given to the experimental group. There were three experimental groups receiving three different doses of purple sweet potato. The mice kidney was taken as sample for microscopic examination to determine the extent of tissue damage. Difference in renal tissue damage was tested by Kruskal-Wallis. Results: Microscopic examination showed statistically significant difference in tissue damage both in right (p=0.001) and left (p=0.036) kidneys, between study groups. The experimental groups showed less damaged than control group. Conclusion: Purple sweet potato (Ipomoiea batatas L) can lessen renal damage in male white mice (Mus musculus L) undergoing excessive physical exercise.

BACKGROUND: Physical exercise can improve antioxidant defense system of an organism, but this process may take a long time. Heavy exercise may disrupt oxidant-antioxidant balance. Low glutathione peroxidase is a biomarker for free radicals. Plant purple sweet potato (Ipomoea batatas L.) contains high anthocyanin that may act as an antioxidant. This study aimed to determine the effect of purple sweet potato extract on the activity of glutathione peroxidase in the liver of mice (Mus Musculus) treated with maximum physical exercise (MPE). SUBJECT AND METHODS: This was a randomized controlled trial using a sample of 24 white DD Webster strain male mice. This sample of mice was randomized into 6 groups: P1-control, P2-MPE, P3-0.5 ml purple sweet potato, P4-MPE + 0.5 ml purple sweet potato, P5-MPE + 1 ml purple sweet potato, and P6-MPE + 1.5 ml purple sweet potato. The purple sweet potatoes were given for 14 days. Difference in means of glutathione peroxidase among the study groups was tested by Kruskal-Wallis. RESULTS: After 14 days of intervention, the level of glutathione peroxidase (mean ± SD in mU/ml) among the study groups were as follows: P1 (6.58±7.04), P2 (1.84±0.92), P3 (4.50±4.31), P4 (7.05±8.19), P5 (19.39±7.06), P6 (3.03±1.98). The highest level of glutathione peroxidase was attained in group P5 with moderate dose (1 ml) of purple sweet potato extract. CONCLUSION: Moderate dose (1 ml) of purple sweet potato extract can effectively increase glutathione peroxidase enzyme in mice.

Damage to the muscle cell acute and chronic can be caused by strenuous physical exercise. Oxidative stress that occurs during strenuous exercise contributes to muscle cell damage. One indicator of muscle cell damage is creatine kinase in the blood serum. Natural antioxidant can be given to counteract the free radicals and reduce oxidative stress. Virgin coconut oil is a natural plant that has potential as an antioxidant. The purpose of this study was to determine the effect of virgin coconut oil on muscle damage by looking at the creatine kinase activity during submaximal exercise in non-athlete students. This is an experimental study with a randomized control group pretest-posttest design. The sample in this study were ten people who were divided into two groups. The control group was given a placebo while the experimental group was given virgin coconut oil at a dose of 15 ml. All groups received submaximal physical exercise with an intensity of 80-90%, a frequency of 3 times a week for one month. Creatine kinase was measured before and after treatment. The creatine kinase activity in the control group increased significantly while the experimental group decreased insignificantly. Virgin coconut oil in this study significantly reduced creatine kinase activity. The antioxidant potential of virgin coconut oil can repair muscle damage in non-athlete students receiving submaximal physical exercise.