Background Primary dysmenorrhea is considered as one of the women’s main problems during reproductive age. The present study aimed to investigate the effect of vitamin D on the severity of dysmenorrhea and menstrual blood loss. Methods This double-blind, randomized, placebo-controlled trial, was performed on 84 single female college students between 18 and 25 years old who living in dormitories. Students with primary dysmenorrhea and vitamin D deficiency were divided into experimental (n = 42) and control (n = 42) groups. Five days before the putative beginning of their next menstrual cycle, the experimental group received 300,000 IU vitamin D (50,000 IU, two tablets every 8 h), and the control group received a placebo (oral paraffin). The effects of the supplement on the severity of dysmenorrhea and menstrual blood loss were evaluated one cycle before and during two successive cycles. Using the visual analog scale (VAS), verbal multidimensional scoring system (VMS), and pictorial blood assessment chart (PBLAC) questionnaires. Fisher’s exact, Chi-square, independent sample t-test and repeated measurements were used. Results In total, 78 of the 84 students completed the study (39 students per group). The intervention resulted in a significant reduction in the mean scores of both the VAS and VMS in the experimental group, in the first and second menstrual cycles (p < 0.001, p < 0.001, respectively), but not in the means score of PBLAC. Mefenamic acid consumption at the first and second menstruation period, in the experimental group was lower than the control group (p = 0.009, p < 0.001, respectively). Conclusions The results indicate that vitamin D supplementation could decrease the severity of primary dysmenorrhea and the need to consume pain-relief medications. Contrariwise vitamin D supplementation had no significant effect on menstrual blood loss. Trial registration This trial was registered in the Iranian Registry of Clinical Trials with code IRCT201305212324N on 18/1/2014. URL of registry: https://en.irct.ir/trial/1964.

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Background: Sleep quality and fatigue have been documented as a challenge for college students, with reports indicating impacts on daytime functioning and academic achievement. The present study evaluates the effect of Pilates exercise on sleep and fatigue among female student residents in the dormitory.Methods: This quasi-experimental study involving 67 participants consisted of one experimental group (assigned Pilates exercise) and one control group. Participants in the experimental group received three one-hour sessions of Pilates exercise weekly for eight-week. Sleep quality and fatigue levels were measured by the Pittsburgh Sleep Quality Index (PSQI) and standard Multidimensional Fatigue Inventory (MFI-20), respectively. These variables were assessed at baseline, weeks four and eight of the study.Results: After four and eight weeks, findings showed an improvement in the sleep quality score (p < 0.001 and p < 0.0001, respectively). After four weeks of intervention, the mean score of the subjective sleep quality and daytime dysfunction in the Pilates group was significantly less than the control group (p < 0.001 and p < 0.002, respectively). Eight weeks of intervention had an additional effect on sleep duration and habitual sleep efficiency (p < 0.04 and p < 0.034, respectively). Also, Pilates exercise significantly reduced the total score of fatigue and its dimensions in weeks four and eight, compared to the control group (p < 0.001).Conclusions: Eight weeks of the Pilate's exercises had a significant improvement in most components of sleep quality; however, the effect of Pilates exercise on fatigue was evident from week four of the intervention.Trial registration: The study was registered on 6/2/2015 in the Iranian Registry of Clinical Trials (IRCT) with IRCT201412282324N15.