Chrysanthemum sp. is a plant often used by the community as an ornamental plant, drink, and traditional medicine. This study aims to examine the plant Chrysanthemum sp. from the aspect of phytochemical and pharmacological activity. The review method used in this study is the PRISMA method. Sources of data obtained using databases electronic from PubMed and Google Scholar. This review shows that plants Chrysanthemum sp. have phytochemical and pharmacological potential. The compounds contained in theplant Chrysanthemum sp. are morphine, genistein, hydantoin, limonene, g-terpinene, a-pinene, a-terpenyl acetate, 4-terpenyl acetate, a-calacorene, a-cedrene, b-bourbobene, elemol, 2- hexenal, and orphenadrine. Chrysanthemum sp. plants have anticancer, antibacterial, antioxidant, antifungal, analgesic, anti-inflammatory, and anticonsulvan activities.

Increasing sexual reproductive health information and knowledge about Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome in adolescents is one of the targets of the Sustainable Development Goals, 2030. The use of sexual education applications helps educate adolescents that supports the achievement of these targets. This study describes the effect of sexual health education applications on adolescent knowledge and decreases the prevalence of Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome to support the 2030 Sustainable Development Goals. This research is a literature study of articles published in NCBI, Google Scholar, and PubMed. The keywords used in the article search were: sex education, android application, Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome, and reproduction health. Inclusion criteria were articles published in 2016-2020, using English or Indonesian, original article, can be accessed in full text, free of charge and the manuscript content’s were relevant to the study. Review articles and duplicate journals were excluded. In this study, only ten of the 1250 articles met the inclusion criteria. Study shows that sexual education applications can increase adolescents' understanding of reproductive health, good and healthy sexuality, improve sexual attitudes and behavior, and also reduce the prevalence of Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome that supports the 2030 Sustainable Development Goals.