The aim of this study is to assess the accuracy of microalbuminuria (MA) to predict the mortality in pediatric intensive care unit (PICU). Between December 2014 and November 2015, 250 patients who were 1 month to 18 years old monitored at least 24 hours in PICU and met study criteria were included. Spot urine samples were measured for microalbuminuria. Pediatric Risk of Mortality III-24 and Pediatric Multiple Organ Dysfunction scores were calculated by using the worst parameters in first 24 hours. The collected data were analyzed with statistical methods and compared with mortality scoring systems and observed mortality. MA values were significantly higher in nonsurvivors than the average of the survivors (18 vs. 48 mg/g, p < 0.05). The receiver operating characteristics curve analysis showed that the areas under the curves for MA was 0.81 at a cut-off value of 32 mg/g, MA measured in 24 hours of admission to PICU may be able to discriminate between patients a with sensitivity of 85.2, specificity of 70.8%, positive predictive value of 31.5%, and negative predictive value of 96.8%. MA is a useful tool to predict mortality in PICU.

Amaç: Bu çalışmanın amacı çocuk yoğun bakım ünitesine yatış sırasındaki hemoglobin düzeyi ve izlem sırasında eritrosit transfüzyonu gereksinimi ile mortalite arasındaki ilişkinin araştırılmasıdır. Yöntemler: Bu ileriye yönelik çalışmaya on iki yataklı çocuk yoğun bakım ünitesine bir yıl süreyle kabul edilen toplam 260 hasta dahil edilmiştir. Hastaların demografik özellikleri, yatış nedenleri, yatış süreleri, mekanik ventilatör gereksinimi ve mekanik ventilatörde kalma süreleri, pediyatrik mortalite riski III ve pediyatrik lojistik organ disfonksiyon skorları, yatış anındaki tam kan sayımı değerleri ile transfüze edilme durumları kayıt edildi. Bulgular: Çalışmaya alınan hastalardan 34 olgu eksitus oldu. Çalışmamızda kaba mortalite oranı %13 idi. Eksitus olan hastaların ortalama hemoglobin düzeyleri (10,55±2,45 g/dL) sağ kalan hastaların değerlerine (11,58±2,15 g/dL) göre daha düşük bulundu (p=0,011). Transfüzyon uygulanan hastaların mortalite oranı transfüze edilmeyen hastalara göre anlamlı olarak yüksek bulundu (%40,2 vs. %1,6; p<0,001). Sonuç: Çalışmamızda kritik çocuk hastalarda çocuk yoğun bakım ünitesine başvuru sırasında anemi varlığı ve/veya takip sırasında transfüzyon gereksinimi artmış mortalite riski ile ilişkili bulunmuştur. Anahtar Kelimeler: Çocuk yoğun bakım, anemi, transfüzyon, mortaliteIntroductıon: This study aimed to investigate the relationship of hemoglobin concentration at admission to pediatric intensive care unit and erythrocyte transfusion during hospitalization with mortality. Methods: In this prospective study, we included 260 patients who were admitted to a 12-bed pediatric intensive care unit in a one-year period. Demographic characteristics, admission etiologies, length of stay in the pediatric intensive care unit, mechanical ventilation rates, pediatric risk of mortality III and pediatric logistic organ dysfunction scores, complete blood count on admission and erythrocyte transfusion during hospitalization were recorded prospectively. Results: Of the 260 cases, 34 were exitus. The mortality rate was 13%. The mean hemoglobin concentration of patients who were exitus was lower than that of patients who survived (10.55±2.45 g/dL vs. 10.55±2.45 g/dL, p=0.011). Although platelet levels were lower in patients who were exitus than in survivors, the difference was not statistically significant (320.352±181.731/mm 3 vs. 352.231±174,129/mm 3 p=0.325). The mortality rate in transfused patients was higher than in patients who were not transfused. (40.2% vs. 1.6%, p<0.001). Conclusion: Hemoglobin concentration at admission in patients who die in pediatric intensive care unit is significantly lower than in those who survive. In this study, increased mortality risk in patients admitted to pediatric intensive care unit was found to be associated with the presence of anemia and need for erythrocyte transfusion.

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