Organ preservation by heavy water (D 2 O) Morphological and biochemical studies on heart and liver Summary:The tissue H 2 O of rabbit heart and rat liver was partially exchanged in situ with D 2 O. In rat liver, the loss of ATP, resulting from normpthermic ischemia, was decreased after perfusion with D 2 O. The maximal protective effect was found when the proportion of D 2 0 in the water of the liver tissue was 0.20. In both organs the protective effect of D 2 O could be correlated with a marked x decrease in severe ischemic damage of cellular organelles, in particular mitochondria. D 2 O also increased the protective action of Mg-ions in the heart. Einleitung

No abstract

No abstract

No abstract

No abstract