Extracorporeal membrane oxygenation (ECMO) may offer life-saving treatment in severe pulmonary contusion or acute respiratory distress syndrome when conventional treatments have failed. However, because of the bleeding risk of systemic anticoagulation, ECMO should be performed only as a last resort in multiple trauma victims. Here, we report ECMO as a bridge for right main bronchus reconstruction and recovery of traumatic wet lung in a 31-year-old male multi-trauma patient with right main bronchial disruption, bilateral pulmonary contusion, cerebral contusion and long bone fracture. The patient was discharged without any obvious complication. ECMO support in a traumatic brain injured patient with severe hypoxemia caused by lung contusion and/or tracheal bronchus disruption is not an absolute contraindication.
Background and aims: Inflammatory key receptor TLR4 has been proved to be critical in the pathogenesis of necrotizing enterocolitis (NEC).Latest study revealed TLR4 also mediate apoptotic pathways. This study was to investigate the new role of TLR4 as a mediator for inflammation-apoptosis signaling pathways in NEC.
preprandial values on day 15 (mean [SD]: from 66%[11] to 64% [11], p = 0.091). Conclusion Our results suggest that in preterm infants during their first 36 days of life, cerebral perfusion does not decrease the first hour after feeding. One might reason that most preterm infants may yet be able to regulate cerebral perfusion, or postprandial intestinal perfusion may not increase at all. Background Term born infants demonstrate an increase in intestinal perfusion after receiving enteral feeding (postprandial intestinal hyperemia). It remains unclear whether enteral feeding influences intestinal perfusion in preterm infants. Aim To assess the effect of enteral feeding on intestinal perfusion in preterm infants. Methods This study was part of a larger prospective cohort study. We used near-infrared spectroscopy to measure regional intestinal oxygen saturation (r int SO 2 ), which is indicative for intestinal perfusion. We measured during two hours on postnatal Conclusion Our results suggest that in preterm infants during their first three weeks of life, intestinal oxygen saturation does not increase, and sometimes even decreases, the first hour after feeding. One might speculate that preterm infants are not yet able to increase intestinal perfusion rates after feeding, an increase which might be necessary to meet metabolic demands.
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