SUMMARY Plasma bilirubin was estimated on 690 term infants on about the 6th day of life. Perinatal factors were recorded and the results analysed. Hyperbilirubinaemia was defined as a level >205,umol/l (12 mg/100 ml) and this was present in 20% of cases. Three factors-epidural analgesia, breast feeding, and poor weight recovery-showed highly significant associations with jaundice. The relative importance of these is discussed and compared with recent reports. Induction of labour, for reasons other than postmaturity, and a gestational age <39 weeks showed a slightly increased incidence of jaundice. There was no correlation with other factors tested including oxytocic drug administration. Despite the high incidence (20 %) of hyperbilirubinaemia, only 2.5 % infants needed treatment and none required exchange transfusion. Radical (Ghosh and Hudson, 1972;Davidson et al., 1973;Eden et al., 1974;Gould et al., 1974;Chalmers et al., 1975

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Two parameters of connective tissue metabolism, viz. urinary hydroxyproline and urinary glycosaminoglycans, have been studied in newborn babies. A characteristic pattern is discernible, which is probably related to the rate of growth. The precise clinical value of these observations is yet to be determined, but it seems probable that they will provide a useful assessment of 'chemical growth' in the newborn.