Random aliphatic copolymers synthesized by direct melt polycondensation reaction between Polyethylene glycol dodecanediol succinate (PEDDSU) and Polyethylene glycol dodecanediol sebacate (PEDDSE). This reaction occurred with titanium tetra-isopropoxide Ti(ipo)4 as a catalyst. The characterization studies were examined by IR Spectroscopy, Nuclear magnetic resonance (NMR), Thermal analysis (DSC), Wide angle x-ray diffraction (WAXD) and molecular weight determination by Gel permeation chromatography (GPC). The viscosity and solubility studies are also measured for the newly synthesized copolyesters. Inherent viscosities were studied using ubbelholde viscometer. The addition of methylene units in the di-acid results in a decrease of Tm and Tg from the DSC analysis of copolyesters. The studies on number average and weight average molecular weight of these copolyesters have confirmed their molecular weights. We have also studied the anticancer activity of these copolyesters which were tested against VERO and MCF-7 cell lines. The results of these studies conclude that both the obtained copolymers showed tremendous activity towards the anticarcinogenic property.

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