Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.

L’accident vasculaire cérébral (AVC) se définit comme le développement rapide de signes cliniques localisés ou globaux de dysfonction cérébrale sans autre cause apparente qu’une origine vasculaire. Différents facteurs de risque ont été identifiés et associés à la survenue des AVC ischémiques dont les perturbations du métabolisme glucidique et lipidique. Nous avons mené une étude rétrospective à la clinique neurologique de Fann. Notre étude a porté sur les dossiers des patients hospitalisés du 1er Janvier au 31 Décembre 2010 pour un AVCI confirmé par l’imagérie. Tous nos patients avaient beneficié d’un bilan lipidique complet (cholestérol total, triglycérides, HDL ; le taux de LDL ayant été calculé grâce à la formule de Friedwald, d’un bilan rénal et d’une glycémie à jeun prélevés dans les 48 heures suivant l’admission. Les données ont été analysées en mesure univariée, ensuite bivariée grace au logiciel SPSS 16.0. Nous avons colligé 235 dossiers. Les patients étaient âgés de 10 à 99 ans avec une moyenne à 67,06 ans. Le sexe masculin était à 42,55%, le sex-ratio était de 0,74 en faveur des femmes. Vingt Six pour cent avaient une glycémie à jeun anormale à la phase aiguë de l’AVCI. Le bilan lipidique montrait une augmentation du cholestérol total chez 52,34% des patients. Le HDL était bas chez 34,47% des patients. L’hypertriglycéridémie n’avait été observée que chez 3% des patients. Le LDL était élevé chez 12,76%. L’indice d’athérogénicité était élevé chez 25,53% des patients. Des perturbations de la glycémie et du bilan lipidique sont très souvent associées à l’AVCI et doivent être prises en compte pour assurer une meilleure prévention secondaire.

Migraine-related disability is multidimensional and is poorly appreciated by the diagnostic criteria of the International Society of Headache. The Headache Impact Test-6 (HIT 6) and the Migraine Disability Assessment Questionnaire (MIDAS) are the main scales validated in order to assess the burden associated with migraine. We wanted through this study prospective, transversal, determine the disability associated with migraine in the Mauritanians. The study concerned migraine patients according to the criteria of the International Society of Headache (2013), accepting any treatment. The impact of the disease has been appreciated by the MIDAS and HIT6 scales. Seventy four (74) migrainous have been included. The average age was 30 years and the sex ratio of 3.6 (F/H). All patients have noted a decrease in productivity in relation to migraines. The loss of productivity per quarter was more than 20 days in 78.60% of cases, between 10 and 20 days in 11, 80%, 6-10 days in 6.20% and less than 6 days in 3.40%. The impact of migraine was major in 90, 54% of migraineurs according to the HIT6. The impact of migraine on the quality of life of the Mauritanian patient is huge. Due to the high productivity loss, migraine can be an impediment to the development where the need to encourage physicians to training on the management of pain and put in place support units dedicated to pain.

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Dementia is a serious disease due to its morbidity and mortality. The etiology is dominated by Alzheimer's disease.However, there are dementia syndromes related to treatable and potentially curable cause. It's rarely reported in clinical practice in our context. We report a case of dementia associated with lymphoblastic acute leukemia complicated by lymphocytic meningitis. F. ND aged 66, widow, unschooled and unemployed was hospitalized for gait disturbance and progressive appearance of memory disorders. On physical examination, there was a dementia syndrome, bilateral pyramidal syndrome. The rest of the clinical examination associated with additional tests (thoraco-abdominal-pelvic CT scan, lumbar puncture, and myelogram) was in favor of lymphocytic meningitis and acute lymphocytic leukemia. Dementia is a disease in which the search for the cause is crucial for considering an etiological support. Blood diseases such as LAL are treatable causes. The clinic provides a guidance element of research. Also, multidisciplinary care is necessary in these kinds of patients for a better development. This scientific cooperation must be done with, hematologists, internal medicine specialists and other colleagues.