BACKGROUND: Recently, stroke therapy is focused on reperfusion therapies for restoring cerebral blood flow (CBF) and minimizing the undesired effects of neuron ischemia. However, the thrombolytic therapy to restore CBF was restricted with narrow time window. On other hands, not many patients can reach the treatment immediately after the onset of stroke. A wider time window therapy that might increase CBF would probably helpful. This study aims to investigate the CBF improvement after intra arterial heparin flushing (IAHF) therapy in chronic stroke patients.METHODS: A clinical trial was conducted with time sampling. We collected chronic ischemic stroke subjects (with stroke onset ≥30 days) within periods February-September 2015. We investigated CBF before and after IAHF treatment in 75 chronic stroke patients. The difference before and after IAHF treatment in subgroup which is classified with infarct size and lesion area was tested. CBF was measured using MRI Quality Arterial Spin Labeling (qASL) with region of interest around infarct lesion.RESULTS: We found a significant CBF improvement (p<0.001) around infarct area after IAHF treatment with average 10.39mL/100g/min raised. CBF improvement was found in lacunar infarct (p<0.001) and non lacunar (p<0.001), also in infarct in cortical (p<0.05), subcortical (p<0.001) and both area (p<0.05).CONCLUSION: IAHF is associated with increased CBF around infarct area and IAHF probably offers some benefit for chronic stroke.KEYWORDS: IAHF, CBF, chronic stroke, ischemic, lacunar, non lacunar, cortical lesion, subcortical lesion

B ACKGROUND: The conventional magnetic resonance imaging (cMRI) and apparent diffusion coefficient (ADC) may have a role in predicting tumor grade for gliomas and may in turn assist in identifying tumor biopsy sites. In this study, we aimed to determine the added value of a joint approach of diffusion-weighted imaging (DWI) and cMRI to determine of low grade and high-grade glioma, compare to cMRI alone. METHODS:Data were collected from 56 glioma patients, who underwent examinations and received treatment at Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia, from the period of 2015-2018. Inclusion criteria was patients who underwent cMRI with a DWI-ADC sequence and patient that were diagnosed with glioma according to the histopathological results. Pathology reports of the imaging results were reviewed independently.A receiver operator curve (ROC) analysis assessed the predictive potential of cMRI and ADC values for low-grade and high-grade gliomas. RESULTS:Fifty-six subjects met the inclusion criteria. The combination of MRI and ADC values increased sensitivity (to 90%) and negative predictive value (to 92.9%), and also improved the negative likelihood ratio (to 0.14). However, the combination of MRI and ADC values had the highest area under the curve (78.6%) and sensitivity (78.6%), which was similar to the separated examination. CONCLUSION:The combination of ADC value and conventional MRI increases sensitivity in differentiating low-grade and high-grade glioma compared to separated examination. Abstract IntroductionGliomas are the most common primary brain tumors in adults. Glial tumors are made up of astrocytomas, oligodendrogliomas, mixed oligo-astrocytic, and mixed glioneuronal tumors, which arise from the supporting glial cells of the central nervous system (CNS).(1) According to the Central Brain Tumor Registry of the United States (CBTRUS) Statistical Reports, there were 392,982 cases of

Penelitian ini bertujuan untuk menilai korelasi ketebalan tunika intima-media arteri karotis pada ultrasonografi, kalsifikasi dan dilatasi pada arkus aorta pada foto thorax posisi PA dengan nilai renal resistive index menggunakan ultrasonografi duplex pada pasien hipertensi. Penelitian ini dilaksanakan di Departemen Radiologi Rumah Sakit Umum Pemerintah Wahidin Sudirohusodo Makassar dan Rumah Sakit Pendidikan Universitas Hasanuddin Makassar mulai bulan Desember 2019 sampai bulan Maret 2020. Sampel sebanyak 60 pasien dengan usia ? 18 tahun. Metode yang digunakan adalah uji korelasi Spearman rho. Hasil penelitian menujukkan bahwa ada korelasi signifikan (p 0,05) antara kalsifikasi aorta p=0,0001 dan nilai CIMT p=0,0001 dengan nilai index resistive renal bilateral. Terdapat korelasi signifikan antara pasien hipertensi riwayat dislipidemia yang disertai penebalan tunika intima media arteri karotis p = 0,025, kalsifikasi pada arkus aorta p=0,001 dan dilatasi aorta p=0,003 dengan nilai index resistive renal bilateral. Tidak ada korelasi antara dilatasi aorta dengan dengan nilai index resistive renal bilateral.

In the past, dental implant (DI)treatment is still an exclusive treatment can only beachieved by high class people due to unaffordable cost. However, nowadays thedemand of DI become increasing. The success of DI insertion is determined by thecondition of alveolar bone itself. Although there is no studies of DI treatment failurein Indonesia, there are some reports studied failure of DI treatment assessment whichcould be caused by the lack of quality and quantity of the alveolar bone radiographyimage. The purpose of this article was to introduce the benefit of hounsfield unit at theCT-Scan in supporting assessment of alveolar bone compactness for DI insertion. Itcan be concluded that the use of hounsfield unit at the CT-Scan can provide theclinician in determining the alveolar bone compactness prior to the DI treatment thatcan decrease the failure to occur.

Penelitian ini bertujuan mengetahui korelasi derajat leukoaraiosis berdasarkan CT-Scan kepala dengan faktor-faktor risiko stroke dan keparahan stroke berdasarkan derajat klinis pada pasien stroke iskemik. Metode yang digunakan adalah cross sectional, dilakukan secara retrospektif pada penderita stroke iskemik yang menjalani pemeriksaan CT-Scan kepala di Bagian Radiologi RSUP dr. Wahidin Sudirohusodo, Makassar periode Januari 2020 sampai Juli 2020. Sampel sebanyak 46 orang dengan usia 40 tahun yang mengalami serangan stroke pertama dengan onset 1 bulan. Derajat leukoaraiosis dinilai dengan menggunakan skala Van Swieten dan derajat klinis dinilai dengan menggunakan National Institute of Health Stroke Scale (NIHSS). Uji statistik yang digunakan adalah uji korelasi Spearman. Hasil penelitian menunjukkan bahwa ada korelasi bermakna yang sedang dan searah antara derajat leukoaraiosis dan kelompok umur dengan nilai p sebesar 0,004 (0,05) dan nilai r sebesar 0,415. Tidak ada korelasi bermakna antara derajat leukoaraiosis dengan jenis kelamin, hipertensi, diabetes melitus, dislipidemia dan derajat klinis dengan nilai p masing-masing secara berurutan sebesar 0,146; 0,520; 0,779; 0,185; dan 0,537 (0,05). Namun tampak kecenderungan bahwa pasien dengan hipertensi tidak terkontrol memiliki derajat leukoaraiosis yang lebih berat.