Breast cancer is considered one of the major healthcare problems and one of the top biomedical research priorities among all biomedical research. Breast cancer is a common but extremely complex disease. The incidence of breast cancer becoming more aggressive is increasing, with around one million and seven hundred thousand new cases that get worse yearly, and this incidence is expected to increase significantly in the next 5–10 years. These rates are suggestive of the slow progress of this disease. Worldwide, Breast cancer is the most common cancer affecting women. The mortality rates for women who are already diagnosed with breast cancer have improved, but even then, the median survival in the metastatic stage is low, around 24 months. For the treatment, chemotherapy is the gold-standard approach for most cancer types and the modest improvement in both survival rates and toxicity reduction. Every newly diagnosed breast cancer should be presented at a multidisciplinary conference to ensure optimal management by all specialties involved. A careful history of a woman’s risk and symptoms and a thorough physical examination are important in the evaluation of breast problems and appropriately timed imaging and diagnostic studies are also important. Early detection of breast cancer at a stage when it is potentially curable and there is the possibility of saving a breast should be the goal of all health care professionals. Also, careful consideration should be given to the unique nature of each tumor and patient. This article aims to provide a brief introduction and the clinical picture of the disease, Etiology, Pathophysiology, Epidemiology, Nutrition, Prevention, and good practice management advice. Keywords: Breast Cancer, BRCA1 gene, BRCA2 gene, Type one Diabetes mullites. Type Two Diabetes Mellites.

The occurrence of non-alcoholic fatty liver disease has exponentially increased worldwide. A considerable majority of cases advance to non-Alcoholic Steatohepatitis in the nonexistence of therapeutic measures, which increases morbidity and death. Because the initial phases of the illness are frequently clinically unapparent, the identification of non-alcoholic fatty liver disease frequently rests on biochemical and radiographic studies. Concentrated life modifications that result in weight loss are the mainstay of the disease's management. Therapeutic treatments that could be additional to lifestyle changes once essential for case managing comprise insulin sensitizers, antioxidants, incretin-based pharmaceuticals, cholesterol depressing mediators, weight reduction therapies, bariatric surgery, and liver transplantation. For non-alcoholic fatty liver disease to be managed more effectively and lessen its worldwide impact, research must be conducted continuously.