Pathophysiological, pathomorphological and functional changes in the kidneys after left ventricular assist device implantation have not yet been fully understood and represent an actual problem of our time. Changes in renal function following left ventricular assist device implantation have been disclosed in many studies with inconsistent results. Some studies have shown that patients with renal dysfunction after left ventricular assist device implantation had worse outcomes, despite stabilization or even improvement of kidney function during the postoperative period, other studies have shown the progression of chronic kidney disease requiring renal replacement therapy.

Pathophysiological, pathomorphological and functional changes in the kidneys after left ventricular assist device implantation have not yet been fully understood and represent an actual problem of our time. Changes in renal function following left ventricular assist device implantation have been disclosed in many studies with inconsistent results. Some studies have shown that patients with renal dysfunction after left ventricular assist device implantation had worse outcomes, despite stabilization or even improvement of kidney function during the postoperative period, other studies have shown the progression of chronic kidney disease requiring renal replacement therapy.

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В статье приведен литературный обзор, посвященный современным проблемам в трансплантологии почек. Нерешенными проблемами остаются оценка донора, низкая приверженность пациентов иммуносупрессивной терапии и развитие дисфункции трансплантата. Развивающиеся осложнения после трансплантации и иммуносупрессивной терапии требуют междисциплинарного подхода в лечении и наблюдении реципиентов донорской почки. Также необходимо широкое развитие трупного донорства для снижения числа потенциальных пациентов с хронической болезнью почек. The article presents a literature review of contemporary problems in kidney transplantation. Donor evaluation, low adherence of patients to immunosuppressive therapy and the development of graft dysfunction remain as unresolved problems. Developing complications after transplantation and immunosuppressive therapy require an interdisciplinary approach in the treatment and monitoring of recipients of donor kidney. It is also indispensable to the development of cadaveric donation to reduce the number of potential patients with chronic kidney disease.