No abstract

Background: This study reports an easy method of veterinary drug investigation in raw milk, based on QuECHERS extraction followed by RP-HPLC-UV analysis. Use of this benchtop system was motivated by its availability and moderate cost relatively to other sophisticated methods such as LC-MS which are more performant. Methods: This developed method has been optimized and then after validated according to EU legislation, demonstrating good linearity with R²>0.997, acceptable peak resolution within short time (˂9.5 min) and a good recovery of analyzed drugs (OXY, ALZ and IVR, respectively 87.08, 99.02 and 92.01%). Additionally we applied the method to analysis of cow milk, collected in Nouakchott, capital of Mauritania. Results: Obtained results indicates a mixed level of drug use according to targeted molecules. In 42% of sampled farms the anti-parasitics IVR and ALZ were detected whereas the antibiotic OXY was detected in 50%. Conclusion: This investigation shows that 17% of sampled farms exceed European standards for IVR drug.