Three‐component reactions of 5,6‐dihydro‐4H‐pyrrolo[3,2,1‐ij]quinoline‐1,2‐dione with malononitrile, or ethyl cyanoacetate, and cyclic six‐membered or a five‐membered 1,3‐diketone, produce spiro[4H‐pyran‐3,3′‐oxindoles].
Aldol condensation of 5,6‐dihydro‐4H‐pyrrolo[3,2,1‐ij]quinoline‐1,2‐dione with aryl methyl ketones generates 3‐(aroylmethylidene)oxindoles, which react with hydrazine to generate tricyclic spiro[3H‐pyrazole‐3,3′‐oxindoles].
The tricyclic isatin, 5,6‐dihydro‐4H‐pyrrolo[3,2,1‐ij]quinoline‐1,2‐dione (1), reacts with a combination of an aryl cyanomethyl ketone 8 and a 5‐amino‐1‐arylpyrazole 7 to generate spirocyclic products 9.
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