Background: Cancer patients’ increased susceptibility to serious COVID-19 complications can be attributed to the immunosuppressed state caused by the disease and anticancer treatments such as chemotherapy or surgery. Objectives: To assess the effect of COVID-19 pandemic on gynecological cancer patients receiving chemotherapy. Methods: A cross-sectional study was conducted on patients receiving chemotherapy for gynecological cancer between (March 2020 to February 2021) at King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia. Clinical data collected from medical records included patients’ ages, medical history data, cycles of chemotherapy, COVID-19 infection, complications and death. Results: Total of 84 patients were identified. The mean age of studied patients was 53.81 ± 13.76 years, and the most common chronic diseases were HTN (35.7%) and DM (23.8%). The majority of diagnoses were ovarian cancer (41.7%) followed by uterine cancer (33.3%). Of studied patients, 17.9%, 19.1%, 27.4 and 33.3% had I, II , III and IV cancer stages respectively. The mean number of cycles of chemotherapy was 7.14 ± 5.55. 52.4% had first line chemotherapy. 57 percent of patients had delays due to various causes, including COVID-19 infection, and 9 percent of patients had COVID-19 while on therapy. 15 percent of the delays were caused by patients who were affected by Covid-19 while receiving chemotherapy and 2% of the patients died as a result of COVID-19 . Patients with recurrent disease had a significantly higher percentage of patients detected with COVID-19, and all cases detected with COVID-19 died with respiratory failure. Patients who had their chemotherapy delayed had a significantly higher mean number of cycles. Conclusion: Improved communication and management programs are required to keep cancer patients and their healthcare providers connected, as well as to allow cancer patients to survive a pandemic. Key words: Impact, COVID-19, patients, chemotherapy, Jeddah, Saudi Arabia.

Cases of symptomatic diaphragmatic hernia in pregnancy are often misdiagnosed due to the nonspecific presentation and lack of experience, placing pregnant women at risk. This case report discusses the presentation and management of a 17-year-old patient who had congenital diaphragmatic hernia complicated with left pulmonary compression in the third trimester of pregnancy Keywords: Maternal, congenital, diaphragmatic, pulmonary, compression, trimester