Background: Nasal polyposis are considered a sign or a physical finding rather than a disease resulting from a complex process that is found in some individuals, such as people suffering from chronic sinusitis, rhinitis, Kartagener's syndrome, or cystic fibrosis. Sinonasal polyps can have four distinct histological subtypes, which include eosinophilic polyp, chronic inflammatory polyp, hyperplastic polyp, and polyp with stromal atypia. Aim: In this review, we aim to study the presentation, classification and diagnosis of nasal polyps in the light of histopathological findings. Materials and methods: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 2001, through February 2017. The following search terms were used: nasal polyp, inflammation of nasal mucosa, chronic inflammation, histology of nasal mucosa, pathology of nasal polyps. Conclusion: Polyposis does not have histological problems and complications. However, they may be clinically disturbing. Polyps are not classified into allergic and non-allergic, and are rather stratified according to histological findings, making histological investigation crucial for diagnosis.

Introduction: The pathway of glycogen metabolism is regulated by many hormones such as insulin, glucagon, and corticosteroids. Glycogen storage diseases (GSD) most commonly affect muscles, liver, or both and occur in each 20000 to 43000 live birth. They are classified into 12 subtypes, but types I, II, and IX are the most common. Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, from January 2001, through February 2017. The following search terms were used: glycogen storage diseases, Von Gierke disease, Pompe's disease, Cori Disease, Forbes disease, Andersen's disease, McArdle disease, neonatal hypoglycemia, neonatal hepatomegaly. Aim: In this review, we aim to study the genetic basis, diagnosis, presentation, and different management approach to various common types of glycogen storage diseases prevalent in pediatric population. Conclusion: There are no cures for any type of glycogen storage diseases presently. Most treatments are designed to control signs and symptoms. The overall goals are primarily avoiding hypoglycemia, hyperlactatemia, hyperuricemia, and hyperlipidemia. Liver transplantation should be deliberated for patients with GSD type IV and for other progressive hepatic types of GSDs in order to avoid hepatic failure or malignancy. More research must be carried out to develop newer and more effective ways of management.

Background: psoriasis is a papulo-squamous disease with different morphology, severity, distribution and course of disease. The aim of the treatment was to reduce disease activity to a level that permits an acceptable quality of life with negligible toxicity from the treatment itself. About 25% of patients experience major psychological distress due to the disease. Its long duration along with comorbidities have a negative impact on quality of life. Aim of the work: we tried to understand the types, pathogenesis and management of psoriasis, and also try to understand its effect on the quality of life. Methodology: we conducted this review using a comprehensive search of MEDLINE, PubMed and EMBASE from January 1994 to March 2017. The following search terms were used: psoriasis, psoriasis classification, psoriasis management, quality of life in psoriasis patients. Aim of the work: we tried to understand the types, pathogenesis, and management of psoriasis, and also try to understand its effect on the quality of life. Conclusion: due to the chronic course, and its noticeable visibility on skin, many patients suffer from major social and psychological ill effects. In majority of the time the health care providers fail to recognize or treat such comorbidities. Healthcare providers must be educated to offer ways to tackle such issues in the management plan for better results Keywords: psoriasis, pathogenesis of psoriasis, management of psoriasis, impact on quality of life in psoriatic patients.