The efficacy of digital contact tracing against COVID-19 epidemic is debated: smartphone penetration is limited in many countries, non-uniform across age groups, with low coverage among elderly, the most vulnerable to SARS-CoV-2. We developed an agent-based model to precise the impact of digital contact tracing and household isolation on COVID-19 transmission. The model, calibrated on French population, integrates demographic, contact-survey and epidemiological information to describe the risk factors for exposure and transmission of COVID-19. We explored realistic levels of case detection, app adoption, population immunity and transmissibility. Assuming a reproductive ratio R=2.6 and 50% detection of clinical cases, a ~20% app adoption reduces peak incidence by ~35%. With R=1.7, >30% app adoption lowers the epidemic to manageable levels. Higher coverage among adults, playing a central role in COVID-19 transmission, yields an indirect benefit for elderly. These results may inform the inclusion of digital contact tracing within a COVID-19 response plan.
The COVID-19 pandemic exhibits intertwined epidemic waves with anomalous fade-outs characterized by persistent low prevalence. These long-living epidemic states complicate epidemic control and challenge current modeling approaches. Here we introduce a modification of the Susceptible-Infected-Recovered model in a meta-population framework where a small inflow of infected individuals accounts for undetected imported cases. Focusing on a regime where this external seeding is so small that cannot be detected from the analysis of epidemic curves, we find that outbreaks of finite duration percolate in time, resulting in overall low but long-living epidemic states. Using a two-state description of the local dynamics, we can extract analytical predictions for the phase space. The comparison with epidemic data demonstrates that our model is able to reproduce some critical signatures observed in COVID-19 spreading in England. Finally, our findings defy our understanding of the concept of epidemic threshold and its relationship with outbreaks survival for disease control.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.